Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Etoposide | 600MPE | -3.4776 | 0.9383 | -5.1061 | -4.0548 | -5.3558 | 0.9960 | 0.4402 | 0.4596 | 7.2788 |
| Etoposide | HCC2185 | -3.4776 | 0.9059 | -3.9244 | -3.5334 | -5.0698 | 0.5674 | 0.1331 | 0.4882 | 7.7979 |
| Etoposide | HCC3153 | -3.4776 | 0.9895 | -5.2941 | -5.2682 | -5.6006 | 1.3885 | 0.0420 | 0.0461 | 5.9853 |
| Etoposide | LY2 | -3.4776 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.9182 |
| Etoposide | ZR75B | -3.4776 | 0.9583 | -5.6916 | -5.2187 | -6.0929 | 0.3813 | 0.1698 | 0.2738 | 5.8559 |
| Fascaplysin | MCF7 | -4.4776 | 0.9785 | -6.5106 | -6.5102 | -6.6917 | 1.9035 | 0.0000 | 0.0002 | 5.5745 |
| Fascaplysin | SK-BR-3 | -4.4776 | 0.9777 | -6.4881 | -6.4810 | -6.6994 | 1.1708 | 0.0110 | 0.0184 | 5.5640 |
| Fascaplysin | MDA-MB-231 | -4.4776 | 0.9406 | -6.5876 | -6.5862 | -6.6577 | 2.9670 | 0.0058 | 0.0059 | 5.6606 |
| Fascaplysin | AU565 | -4.4776 | 0.9859 | -6.8296 | -6.8296 | -6.9778 | 1.3645 | 0.0002 | 0.0009 | 5.1441 |
| Fascaplysin | BT-20 | -4.4776 | 0.9808 | -6.4066 | -6.4041 | -6.5249 | 3.5910 | 0.0068 | 0.0068 | 5.8166 |
| Fascaplysin | BT-474 | -4.4776 | 0.9875 | -6.4501 | -6.4491 | -6.6871 | 2.8135 | 0.0037 | 0.0038 | 5.7197 |
| Fascaplysin | BT-483 | -4.4776 | 0.9919 | -7.0166 | -7.0138 | -7.2225 | 3.7420 | 0.0125 | 0.0125 | 4.8829 |
| Fascaplysin | BT-549 | -4.4776 | 0.9726 | -6.3291 | -6.3287 | -6.3581 | 3.2605 | 0.0013 | 0.0014 | 6.1230 |
| Fascaplysin | CAMA-1 | -4.4776 | 0.9888 | -6.4531 | -6.4524 | -6.5899 | 3.3070 | 0.0035 | 0.0035 | 5.7139 |
| Fascaplysin | HCC1143 | -4.4776 | 0.9804 | -6.4486 | -6.4482 | -6.5516 | 2.2170 | 0.0000 | 0.0000 | 5.7131 |
| Fascaplysin | HCC1395 | -4.4776 | 0.9894 | -6.3281 | -6.3267 | -6.5158 | 2.4265 | 0.0037 | 0.0037 | 5.8352 |
| Fascaplysin | HCC1419 | -4.4776 | 0.9860 | -6.2211 | -6.2182 | -6.5757 | 2.6580 | 0.0085 | 0.0087 | 5.9221 |
| Fascaplysin | HCC1428 | -4.4776 | 0.9933 | -7.2466 | -7.2446 | -7.4391 | 2.6515 | 0.0054 | 0.0054 | 4.4905 |
| Fascaplysin | HCC1569 | -4.4776 | 0.9831 | -6.2996 | -6.2991 | -6.3953 | 2.3550 | 0.0024 | 0.0024 | 5.8015 |
| Fascaplysin | HCC1806 | -4.4776 | 0.9717 | -6.5146 | -6.5131 | -6.5995 | 2.3115 | 0.0053 | 0.0053 | 5.5217 |
| Fascaplysin | HCC1937 | -4.4776 | 0.9884 | -6.3396 | -6.3380 | -6.4588 | 2.5715 | 0.0056 | 0.0057 | 5.8011 |
| Fascaplysin | HCC1954 | -4.4776 | 0.9839 | -6.4836 | -6.4839 | -6.5772 | 2.5395 | 0.0000 | 0.0000 | 5.5274 |
| Fascaplysin | HCC202 | -4.4776 | 0.9784 | -7.1416 | -7.1400 | -7.3198 | 3.9830 | 0.0068 | 0.0068 | 4.8672 |
| Fascaplysin | HCC38 | -4.4776 | 0.9742 | -6.4461 | -6.4462 | -6.5732 | 2.1780 | 0.0000 | 0.0001 | 5.3893 |
| Fascaplysin | HCC70 | -4.4776 | 0.9766 | -6.5836 | -6.5841 | -6.9057 | 1.5250 | 0.0000 | 0.0006 | 5.2074 |