Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Fascaplysin | Hs 578T | -4.4776 | 0.8815 | -6.1351 | -6.1350 | -6.1576 | 3.9980 | 0.0000 | 0.0000 | 6.8170 |
| Fascaplysin | MB 157 | -4.4776 | 0.9257 | -6.8596 | -6.8594 | -6.9090 | 2.5960 | 0.0000 | 0.0000 | 5.4423 |
| Fascaplysin | MDA-MB-134-VI | -4.4776 | 0.9267 | -6.3986 | -6.3988 | -6.6442 | 1.9000 | 0.0000 | 0.0002 | 5.4362 |
| Fascaplysin | MDA-MB-157 | -4.4776 | 0.9457 | -6.5211 | -6.5212 | -6.7578 | 1.9595 | 0.0000 | 0.0001 | 5.3349 |
| Fascaplysin | MDA-MB-175-VII | -4.4776 | 0.9647 | -6.4386 | -6.4390 | -6.6543 | 2.7690 | 0.0000 | 0.0000 | 5.4065 |
| Fascaplysin | MDA-MB-361 | -4.4776 | 0.9925 | -7.0436 | -7.0411 | -7.1518 | 3.9990 | 0.0040 | 0.0040 | 4.9497 |
| Fascaplysin | MDA-MB-436 | -4.4776 | 0.9447 | -6.3926 | -6.3844 | -6.4753 | 2.3840 | 0.0231 | 0.0231 | 6.2197 |
| Fascaplysin | MDA-MB-453 | -4.4776 | 0.9766 | -6.7916 | -6.7919 | -7.0851 | 1.2255 | 0.0000 | 0.0015 | 5.1059 |
| Fascaplysin | MDA-MB-468 | -4.4776 | 0.9901 | -6.9081 | -6.9059 | -6.9905 | 2.6085 | 0.0080 | 0.0080 | 4.9375 |
| Fascaplysin | T47D | -4.4776 | 0.9854 | -6.2056 | -6.2051 | -6.3709 | 2.1810 | 0.0000 | 0.0002 | 6.1009 |
| Fascaplysin | UACC-812 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Fascaplysin | UACC-893 | -4.4776 | 0.9920 | -6.4296 | -6.4285 | -6.5724 | 3.9560 | 0.0046 | 0.0046 | 5.6547 |
| Fascaplysin | ZR-75-1 | -4.4776 | 0.9876 | -6.3036 | -6.3012 | -6.4821 | 2.4065 | 0.0064 | 0.0064 | 5.9147 |
| Fascaplysin | 184B5 | -4.4776 | 0.9939 | -6.4566 | -6.4549 | -6.5644 | 3.4105 | 0.0058 | 0.0058 | 5.6477 |
| Fascaplysin | HCC1187 | -4.4776 | 0.9758 | -7.7196 | -7.7192 | -7.9829 | 2.0550 | 0.0021 | 0.0021 | 4.1023 |
| Fascaplysin | MCF 10A | -4.4776 | 0.9668 | -6.4206 | -6.4210 | -6.4700 | 2.9050 | 0.0001 | 0.0002 | 5.8112 |
| Fascaplysin | MCF 10F | -4.4776 | 0.9815 | -6.3996 | -6.3999 | -6.5768 | 2.0720 | 0.0000 | 0.0001 | 5.5879 |
| Fascaplysin | SUM1315MO2 | -4.4776 | 0.9611 | -6.1336 | -6.1327 | -6.3906 | 2.7410 | 0.0059 | 0.0081 | 6.2950 |
| Fascaplysin | SUM149PT | -4.4776 | 0.9776 | -6.3746 | -6.3720 | -6.4522 | 2.5280 | 0.0082 | 0.0082 | 5.8486 |
| Fascaplysin | SUM159PT | -4.4776 | 0.9625 | -6.3636 | -6.3633 | -6.4005 | 1.8710 | 0.0000 | 0.0003 | 6.0962 |
| Fascaplysin | SUM185PE | -4.4776 | 0.9796 | -6.8116 | -6.8116 | -7.2637 | 1.2950 | 0.0000 | 0.0009 | 5.0270 |
| Fascaplysin | SUM225CWN | -4.4776 | 0.9848 | -6.9386 | -6.9375 | -7.2700 | 1.8930 | 0.0038 | 0.0048 | 4.9975 |
| Fascaplysin | SUM229PE | -4.4776 | 0.9915 | -6.3796 | -6.3782 | -6.4457 | 3.6370 | 0.0074 | 0.0074 | 5.8936 |
| Fascaplysin | SUM52PE | -4.4776 | 0.9805 | -6.4616 | -6.4614 | -6.7280 | 1.5690 | 0.0000 | 0.0008 | 5.4847 |
| Fascaplysin | 184A1 | -4.4776 | 0.9829 | -6.3051 | -6.3045 | -6.4382 | 2.4270 | 0.0007 | 0.0007 | 5.9730 |