Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
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| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Ibandronate | 184B5 | -2.8239 | 0.9723 | -3.5250 | -3.5251 | -3.6415 | 2.4920 | 0.0000 | 0.0176 | 7.4721 |
| Ibandronate | HCC1187 | -2.8239 | 0.9680 | -3.8259 | -3.6173 | -3.8494 | 2.0800 | 0.3155 | 0.3211 | 7.4846 |
| Ibandronate | MCF 10A | -2.8239 | 0.8805 | -3.3611 | -3.3445 | -3.4165 | 1.7210 | 0.0317 | 0.1347 | 8.1046 |
| Ibandronate | MCF 10F | -2.8239 | 0.8695 | -3.5859 | -3.2635 | -3.8306 | 0.7470 | 0.2128 | 0.3800 | 7.7782 |
| Ibandronate | SUM1315MO2 | -2.8239 | 0.9350 | -4.3149 | -4.0774 | -4.3748 | 3.9985 | 0.4378 | 0.4378 | 7.6056 |
| Ibandronate | SUM149PT | -2.8239 | 0.9141 | -3.5458 | -3.5459 | -3.7510 | 0.6664 | 0.0000 | 0.2483 | 7.1631 |
| Ibandronate | SUM159PT | -2.8239 | 0.9294 | -4.4649 | -4.3674 | -4.4007 | 1.8320 | 0.1693 | 0.1701 | 6.6900 |
| Ibandronate | SUM185PE | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Ibandronate | SUM225CWN | -2.8239 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | 8.5431 |
| Ibandronate | SUM229PE | -2.8239 | 0.9274 | -4.3369 | -4.0918 | -4.3004 | 1.1170 | 0.2338 | 0.2491 | 6.9518 |
| Ibandronate | SUM52PE | -2.8239 | 0.9311 | -4.4304 | -4.0989 | -4.5005 | 1.5125 | 0.3355 | 0.3387 | 7.2860 |
| Ibandronate | 184A1 | -2.8239 | 0.9791 | -3.6425 | -3.6426 | -3.8459 | 1.8340 | 0.0000 | 0.0305 | 7.2563 |
| Ibandronate | MCF12A | -2.8239 | 0.9423 | -3.5949 | -3.5393 | -3.7638 | 1.0837 | 0.0623 | 0.1931 | 7.2674 |
| Ibandronate | MX1 | -2.8239 | 0.8565 | -3.8357 | -3.0441 | -3.9733 | 2.0100 | 0.4739 | 0.4857 | 7.8135 |
| Ibandronate | T47DKBLUC | -2.8239 | 0.9630 | -3.9929 | -3.6302 | -3.9984 | 2.6740 | 0.4463 | 0.4467 | 7.9165 |
| Ibandronate | 600MPE | -2.8239 | 0.9601 | -3.8339 | -3.6990 | -3.9054 | 3.9990 | 0.3556 | 0.3557 | 7.6357 |
| Ibandronate | HCC2185 | -2.8239 | 0.8537 | -4.4769 | -3.7133 | -4.9260 | 1.3937 | 0.4318 | 0.4375 | 7.4788 |
| Ibandronate | HCC3153 | -2.8239 | 0.9610 | -4.0564 | -3.5328 | -4.0956 | 1.6930 | 0.4107 | 0.4156 | 7.6521 |
| Ibandronate | LY2 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Ibandronate | ZR75B | -2.8239 | 0.9095 | -4.0079 | -3.7846 | -3.9599 | 3.2110 | 0.4043 | 0.4044 | 7.5978 |
| Ispinesib | MCF7 | -4.4776 | 0.8900 | -6.6601 | -6.6600 | -7.3871 | 0.4538 | 0.0000 | 0.0930 | 5.3114 |
| Ispinesib | SK-BR-3 | -4.4776 | 0.9843 | -7.5416 | -7.5112 | -7.5940 | 3.3705 | 0.1037 | 0.1037 | 4.5686 |
| Ispinesib | MDA-MB-231 | -4.4776 | 0.9268 | -7.5341 | -7.5046 | -7.5399 | 3.2075 | 0.1241 | 0.1241 | 4.8442 |
| Ispinesib | AU565 | -4.4776 | 0.9911 | -7.6716 | -7.6654 | -7.7173 | 3.9990 | 0.0278 | 0.0278 | 4.1992 |
| Ispinesib | BT-20 | -4.4776 | 0.9307 | -7.6586 | -7.5079 | -7.8227 | 2.0120 | 0.2162 | 0.2162 | 5.0491 |