Ispinesib - Small Molecule (ID:10260-999)
| HMS LINCS ID: |
10260-999
|
| Name: | Ispinesib |
| Alternative Names: | SB-715992 |
| LINCS ID: | LSM-5732 |
| PubChem CID: | 6851740 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 516.23 |
| InChi: | InChI=1S/C30H33ClN4O2/c1-20(2)27(34(17-7-16-32)29(36)23-12-10-21(3)11-13-23)28-33-26-18-24(31)14-15-25(26)30(37)35(28)19-22-8-5-4-6-9-22/h4-6,8-15,18,20,27H,7,16-17,19,32H2,1-3H3/t27-/m1/s1 |
| InChi Key: | QJZRFPJCWMNVAV-HHHXNRCGSA-N |
| SMILES: | CC1=CC=C(C=C1)C(=O)N(CCCN)[C@@H](C2=NC3=C(C=CC(=C3)Cl)C(=O)N2CC4=CC=CC=C4)C(C)C |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-05-06 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
KIF11 | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | KCNH2 |
10 (confirmed non-binding) |
Batch Information for HMSL10260-999-1:
| HMS LINCS Batch ID: | 10260-999-1 |
| Provider: | Cytokinetics |
| Provider Batch ID: | |
| Salt: | 999 |
| Molecular Formula: | |
| Molecular Weight: | |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2012-11-14 |
| Most Recent Update: | 2016-12-02 |
(Kd <100 nM)