Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-61 | 3 | 72 | 1.0 | 14200.0 | 14413.7 | 2222.1 | 0.0 | 0.989 | 0.985 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 1.0 | 13200.0 | 14413.7 | 2222.1 | 0.0 | 0.936 | 0.916 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 1.0 | 14960.0 | 14413.7 | 2222.1 | 0.0 | 1.030 | 1.040 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 3.1623 | 13415.0 | 14413.7 | 2222.1 | 0.5 | 0.947 | 0.931 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 3.1623 | 12946.0 | 14413.7 | 2222.1 | 0.5 | 0.922 | 0.898 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 3.1623 | 12300.0 | 14413.7 | 2222.1 | 0.5 | 0.886 | 0.853 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 3.1623 | 13253.0 | 14413.7 | 2222.1 | 0.5 | 0.939 | 0.919 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 10.0 | 4270.0 | 14413.7 | 2222.1 | 1.0 | 0.274 | 0.296 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 10.0 | 4503.0 | 14413.7 | 2222.1 | 1.0 | 0.299 | 0.312 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 10.0 | 5269.0 | 14413.7 | 2222.1 | 1.0 | 0.377 | 0.366 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 10.0 | 4611.0 | 14413.7 | 2222.1 | 1.0 | 0.311 | 0.320 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | Torin1 | 1 | 72 | 0.001 | 16899.0 | 17793.8 | 2895.7 | -3.0 | 0.961 | 0.950 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.001 | 17143.0 | 17793.8 | 2895.7 | -3.0 | 0.972 | 0.963 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.001 | 17045.0 | 17793.8 | 2895.7 | -3.0 | 0.967 | 0.958 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.001 | 18727.0 | 17793.8 | 2895.7 | -3.0 | 1.040 | 1.050 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.0032 | 16930.0 | 17793.8 | 2895.7 | -2.49 | 0.962 | 0.951 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.0032 | 16716.0 | 17793.8 | 2895.7 | -2.49 | 0.953 | 0.939 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.0032 | 17455.0 | 17793.8 | 2895.7 | -2.49 | 0.985 | 0.981 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.0032 | 17574.0 | 17793.8 | 2895.7 | -2.49 | 0.991 | 0.988 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.01 | 16883.0 | 17793.8 | 2895.7 | -2.0 | 0.960 | 0.949 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.01 | 16472.0 | 17793.8 | 2895.7 | -2.0 | 0.942 | 0.926 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.01 | 16841.0 | 17793.8 | 2895.7 | -2.0 | 0.958 | 0.946 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.01 | 16848.0 | 17793.8 | 2895.7 | -2.0 | 0.959 | 0.947 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.0316 | 13871.0 | 17793.8 | 2895.7 | -1.5 | 0.819 | 0.780 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.0316 | 14721.0 | 17793.8 | 2895.7 | -1.5 | 0.860 | 0.827 | 2.619 | HCC1806 Torin1 0 1 |