Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | Torin1 | 1 | 72 | 0.0316 | 14484.0 | 17793.8 | 2895.7 | -1.5 | 0.849 | 0.814 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.0316 | 16361.0 | 17793.8 | 2895.7 | -1.5 | 0.937 | 0.919 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.1 | 10952.0 | 17793.8 | 2895.7 | -1.0 | 0.662 | 0.615 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.1 | 11328.0 | 17793.8 | 2895.7 | -1.0 | 0.683 | 0.637 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.1 | 11038.0 | 17793.8 | 2895.7 | -1.0 | 0.667 | 0.620 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.1 | 12515.0 | 17793.8 | 2895.7 | -1.0 | 0.749 | 0.703 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.3162 | 8170.0 | 17793.8 | 2895.7 | -0.5 | 0.486 | 0.459 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.3162 | 8686.0 | 17793.8 | 2895.7 | -0.5 | 0.521 | 0.488 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.3162 | 8040.0 | 17793.8 | 2895.7 | -0.5 | 0.477 | 0.452 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 0.3162 | 10121.0 | 17793.8 | 2895.7 | -0.5 | 0.612 | 0.569 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 1.0 | 7653.0 | 17793.8 | 2895.7 | 0.0 | 0.449 | 0.430 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 1.0 | 6667.0 | 17793.8 | 2895.7 | 0.0 | 0.375 | 0.375 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 1.0 | 8477.0 | 17793.8 | 2895.7 | 0.0 | 0.507 | 0.476 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 1.0 | 7917.0 | 17793.8 | 2895.7 | 0.0 | 0.468 | 0.445 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 3.1623 | 6460.0 | 17793.8 | 2895.7 | 0.5 | 0.358 | 0.363 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 3.1623 | 5747.0 | 17793.8 | 2895.7 | 0.5 | 0.299 | 0.323 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 3.1623 | 6769.0 | 17793.8 | 2895.7 | 0.5 | 0.383 | 0.380 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 3.1623 | 6390.0 | 17793.8 | 2895.7 | 0.5 | 0.353 | 0.359 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 10.0 | 4465.0 | 17793.8 | 2895.7 | 1.0 | 0.180 | 0.251 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 10.0 | 4516.0 | 17793.8 | 2895.7 | 1.0 | 0.185 | 0.254 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 10.0 | 4559.0 | 17793.8 | 2895.7 | 1.0 | 0.189 | 0.256 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 1 | 72 | 10.0 | 4292.0 | 17793.8 | 2895.7 | 1.0 | 0.162 | 0.241 | 2.619 | HCC1806 Torin1 0 1 |
| HCC1806 | Torin1 | 2 | 72 | 0.001 | 18903.0 | 18525.7 | 2822.7 | -3.0 | 1.010 | 1.020 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 0.001 | 17557.0 | 18525.7 | 2822.7 | -3.0 | 0.961 | 0.948 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 0.001 | 17677.0 | 18525.7 | 2822.7 | -3.0 | 0.966 | 0.954 | 2.714 | HCC1806 Torin1 0 2 |