Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-108 | 2 | 72 | 1.0 | 15771.0 | 18525.7 | 2822.7 | 0.0 | 0.885 | 0.851 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 1.0 | 16257.0 | 18525.7 | 2822.7 | 0.0 | 0.906 | 0.878 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 1.0 | 16398.0 | 18525.7 | 2822.7 | 0.0 | 0.912 | 0.885 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 3.1623 | 12258.0 | 18525.7 | 2822.7 | 0.5 | 0.718 | 0.662 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 3.1623 | 10872.0 | 18525.7 | 2822.7 | 0.5 | 0.643 | 0.587 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 3.1623 | 12037.0 | 18525.7 | 2822.7 | 0.5 | 0.706 | 0.650 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 3.1623 | 12690.0 | 18525.7 | 2822.7 | 0.5 | 0.740 | 0.685 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 10.0 | 6316.0 | 18525.7 | 2822.7 | 1.0 | 0.345 | 0.341 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 10.0 | 6955.0 | 18525.7 | 2822.7 | 1.0 | 0.394 | 0.375 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 10.0 | 7101.0 | 18525.7 | 2822.7 | 1.0 | 0.405 | 0.383 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 10.0 | 6998.0 | 18525.7 | 2822.7 | 1.0 | 0.397 | 0.378 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.001 | 14758.0 | 14413.7 | 2222.1 | -3.0 | 1.020 | 1.020 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.001 | 13709.0 | 14413.7 | 2222.1 | -3.0 | 0.963 | 0.951 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.001 | 13313.0 | 14413.7 | 2222.1 | -3.0 | 0.942 | 0.924 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.001 | 15073.0 | 14413.7 | 2222.1 | -3.0 | 1.030 | 1.050 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.0032 | 14497.0 | 14413.7 | 2222.1 | -2.49 | 1.000 | 1.010 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.0032 | 12587.0 | 14413.7 | 2222.1 | -2.49 | 0.902 | 0.873 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.0032 | 14139.0 | 14413.7 | 2222.1 | -2.49 | 0.986 | 0.981 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.0032 | 14073.0 | 14413.7 | 2222.1 | -2.49 | 0.982 | 0.976 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.01 | 14343.0 | 14413.7 | 2222.1 | -2.0 | 0.996 | 0.995 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.01 | 14574.0 | 14413.7 | 2222.1 | -2.0 | 1.010 | 1.010 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.01 | 14402.0 | 14413.7 | 2222.1 | -2.0 | 0.999 | 0.999 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.01 | 14839.0 | 14413.7 | 2222.1 | -2.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.0316 | 14110.0 | 14413.7 | 2222.1 | -1.5 | 0.984 | 0.979 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.0316 | 13321.0 | 14413.7 | 2222.1 | -1.5 | 0.942 | 0.924 | 2.697 | HCC1806 QL-XII-108 0 3 |