Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-108 | 2 | 72 | 0.001 | 17924.0 | 18525.7 | 2822.7 | -3.0 | 0.976 | 0.968 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.001 | 17108.0 | 18525.7 | 2822.7 | -3.0 | 0.942 | 0.923 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.001 | 18146.0 | 18525.7 | 2822.7 | -3.0 | 0.985 | 0.980 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.001 | 19628.0 | 18525.7 | 2822.7 | -3.0 | 1.040 | 1.060 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.0032 | 18901.0 | 18525.7 | 2822.7 | -2.49 | 1.010 | 1.020 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.0032 | 18052.0 | 18525.7 | 2822.7 | -2.49 | 0.981 | 0.974 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.0032 | 9870.0 | 18525.7 | 2822.7 | -2.49 | 0.586 | 0.533 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.0032 | 17917.0 | 18525.7 | 2822.7 | -2.49 | 0.976 | 0.967 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.01 | 18251.0 | 18525.7 | 2822.7 | -2.0 | 0.989 | 0.985 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.01 | 18986.0 | 18525.7 | 2822.7 | -2.0 | 1.020 | 1.020 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.01 | 18646.0 | 18525.7 | 2822.7 | -2.0 | 1.000 | 1.010 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.01 | 19154.0 | 18525.7 | 2822.7 | -2.0 | 1.020 | 1.030 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.0316 | 18343.0 | 18525.7 | 2822.7 | -1.5 | 0.993 | 0.990 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.0316 | 17468.0 | 18525.7 | 2822.7 | -1.5 | 0.957 | 0.943 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.0316 | 18868.0 | 18525.7 | 2822.7 | -1.5 | 1.010 | 1.020 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.0316 | 18084.0 | 18525.7 | 2822.7 | -1.5 | 0.982 | 0.976 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.1 | 18911.0 | 18525.7 | 2822.7 | -1.0 | 1.020 | 1.020 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.1 | 17334.0 | 18525.7 | 2822.7 | -1.0 | 0.952 | 0.936 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.1 | 19421.0 | 18525.7 | 2822.7 | -1.0 | 1.040 | 1.050 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.1 | 19665.0 | 18525.7 | 2822.7 | -1.0 | 1.040 | 1.060 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.3162 | 17595.0 | 18525.7 | 2822.7 | -0.5 | 0.962 | 0.950 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.3162 | 17665.0 | 18525.7 | 2822.7 | -0.5 | 0.965 | 0.954 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.3162 | 18084.0 | 18525.7 | 2822.7 | -0.5 | 0.982 | 0.976 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 0.3162 | 17579.0 | 18525.7 | 2822.7 | -0.5 | 0.962 | 0.949 | 2.714 | HCC1806 QL-XII-108 0 2 |
| HCC1806 | QL-XII-108 | 2 | 72 | 1.0 | 16521.0 | 18525.7 | 2822.7 | 0.0 | 0.917 | 0.892 | 2.714 | HCC1806 QL-XII-108 0 2 |