Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-61 | 3 | 72 | 0.001 | 14504.0 | 14413.7 | 2222.1 | -3.0 | 1.000 | 1.010 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.001 | 13254.0 | 14413.7 | 2222.1 | -3.0 | 0.939 | 0.920 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.001 | 14985.0 | 14413.7 | 2222.1 | -3.0 | 1.030 | 1.040 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.001 | 14667.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.020 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.0032 | 14904.0 | 14413.7 | 2222.1 | -2.49 | 1.020 | 1.030 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.0032 | 14745.0 | 14413.7 | 2222.1 | -2.49 | 1.020 | 1.020 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.0032 | 13937.0 | 14413.7 | 2222.1 | -2.49 | 0.975 | 0.967 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.0032 | 15704.0 | 14413.7 | 2222.1 | -2.49 | 1.060 | 1.090 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.01 | 14840.0 | 14413.7 | 2222.1 | -2.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.01 | 13693.0 | 14413.7 | 2222.1 | -2.0 | 0.962 | 0.950 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.01 | 14926.0 | 14413.7 | 2222.1 | -2.0 | 1.030 | 1.040 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.01 | 14799.0 | 14413.7 | 2222.1 | -2.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.0316 | 13420.0 | 14413.7 | 2222.1 | -1.5 | 0.948 | 0.931 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.0316 | 14761.0 | 14413.7 | 2222.1 | -1.5 | 1.020 | 1.020 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.0316 | 15490.0 | 14413.7 | 2222.1 | -1.5 | 1.050 | 1.070 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.0316 | 13828.0 | 14413.7 | 2222.1 | -1.5 | 0.969 | 0.959 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.1 | 14783.0 | 14413.7 | 2222.1 | -1.0 | 1.020 | 1.030 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.1 | 14401.0 | 14413.7 | 2222.1 | -1.0 | 0.999 | 0.999 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.1 | 14372.0 | 14413.7 | 2222.1 | -1.0 | 0.998 | 0.997 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.1 | 14161.0 | 14413.7 | 2222.1 | -1.0 | 0.987 | 0.982 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.3162 | 14661.0 | 14413.7 | 2222.1 | -0.5 | 1.010 | 1.020 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.3162 | 14282.0 | 14413.7 | 2222.1 | -0.5 | 0.993 | 0.991 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.3162 | 15657.0 | 14413.7 | 2222.1 | -0.5 | 1.060 | 1.090 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 0.3162 | 14920.0 | 14413.7 | 2222.1 | -0.5 | 1.030 | 1.040 | 2.697 | HCC1806 QL-XII-61 0 3 |
| HCC1806 | QL-XII-61 | 3 | 72 | 1.0 | 15469.0 | 14413.7 | 2222.1 | 0.0 | 1.050 | 1.070 | 2.697 | HCC1806 QL-XII-61 0 3 |