Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-VIII-58 | 1 | 72 | 1.0 | 5270.0 | 17793.8 | 2895.7 | 0.0 | 0.257 | 0.296 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 3.1623 | 1071.0 | 17793.8 | 2895.7 | 0.5 | -0.316 | 0.060 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 3.1623 | 1058.0 | 17793.8 | 2895.7 | 0.5 | -0.319 | 0.060 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 3.1623 | 950.0 | 17793.8 | 2895.7 | 0.5 | -0.347 | 0.053 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 3.1623 | 852.0 | 17793.8 | 2895.7 | 0.5 | -0.373 | 0.048 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 10.0 | 219.0 | 17793.8 | 2895.7 | 1.0 | -0.627 | 0.012 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 10.0 | 155.0 | 17793.8 | 2895.7 | 1.0 | -0.673 | 0.009 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 10.0 | 181.0 | 17793.8 | 2895.7 | 1.0 | -0.653 | 0.010 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 1 | 72 | 10.0 | 154.0 | 17793.8 | 2895.7 | 1.0 | -0.674 | 0.009 | 2.619 | HCC1806 QL-VIII-58 0 1 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.001 | 17451.0 | 18525.7 | 2822.7 | -3.0 | 0.956 | 0.942 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.001 | 18626.0 | 18525.7 | 2822.7 | -3.0 | 1.000 | 1.010 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.001 | 17843.0 | 18525.7 | 2822.7 | -3.0 | 0.973 | 0.963 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.001 | 19009.0 | 18525.7 | 2822.7 | -3.0 | 1.020 | 1.030 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.0032 | 19096.0 | 18525.7 | 2822.7 | -2.49 | 1.020 | 1.030 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.0032 | 18970.0 | 18525.7 | 2822.7 | -2.49 | 1.020 | 1.020 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.0032 | 18932.0 | 18525.7 | 2822.7 | -2.49 | 1.020 | 1.020 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.0032 | 18496.0 | 18525.7 | 2822.7 | -2.49 | 0.999 | 0.998 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.01 | 18323.0 | 18525.7 | 2822.7 | -2.0 | 0.992 | 0.989 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.01 | 18375.0 | 18525.7 | 2822.7 | -2.0 | 0.994 | 0.992 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.01 | 18125.0 | 18525.7 | 2822.7 | -2.0 | 0.984 | 0.978 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.01 | 15517.0 | 18525.7 | 2822.7 | -2.0 | 0.874 | 0.838 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.0316 | 17803.0 | 18525.7 | 2822.7 | -1.5 | 0.971 | 0.961 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.0316 | 17570.0 | 18525.7 | 2822.7 | -1.5 | 0.961 | 0.948 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.0316 | 4168.0 | 18525.7 | 2822.7 | -1.5 | 0.154 | 0.225 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.0316 | 16581.0 | 18525.7 | 2822.7 | -1.5 | 0.920 | 0.895 | 2.714 | HCC1806 QL-VIII-58 0 2 |