Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.1 | 13793.0 | 18525.7 | 2822.7 | -1.0 | 0.794 | 0.745 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.1 | 8679.0 | 18525.7 | 2822.7 | -1.0 | 0.513 | 0.468 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.1 | 14216.0 | 18525.7 | 2822.7 | -1.0 | 0.814 | 0.767 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.1 | 11858.0 | 18525.7 | 2822.7 | -1.0 | 0.697 | 0.640 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.3162 | 10435.0 | 18525.7 | 2822.7 | -0.5 | 0.619 | 0.563 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.3162 | 10415.0 | 18525.7 | 2822.7 | -0.5 | 0.618 | 0.562 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.3162 | 10308.0 | 18525.7 | 2822.7 | -0.5 | 0.612 | 0.556 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 0.3162 | 9271.0 | 18525.7 | 2822.7 | -0.5 | 0.550 | 0.500 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 1.0 | 5370.0 | 18525.7 | 2822.7 | 0.0 | 0.267 | 0.290 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 1.0 | 5657.0 | 18525.7 | 2822.7 | 0.0 | 0.292 | 0.305 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 1.0 | 4821.0 | 18525.7 | 2822.7 | 0.0 | 0.218 | 0.260 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 1.0 | 5695.0 | 18525.7 | 2822.7 | 0.0 | 0.295 | 0.307 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 3.1623 | 1221.0 | 18525.7 | 2822.7 | 0.5 | -0.266 | 0.066 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 3.1623 | 1074.0 | 18525.7 | 2822.7 | 0.5 | -0.300 | 0.058 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 3.1623 | 1121.0 | 18525.7 | 2822.7 | 0.5 | -0.288 | 0.061 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 3.1623 | 826.0 | 18525.7 | 2822.7 | 0.5 | -0.364 | 0.045 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 10.0 | 129.0 | 18525.7 | 2822.7 | 1.0 | -0.679 | 0.007 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 10.0 | 146.0 | 18525.7 | 2822.7 | 1.0 | -0.664 | 0.008 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 10.0 | 132.0 | 18525.7 | 2822.7 | 1.0 | -0.676 | 0.007 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 2 | 72 | 10.0 | 147.0 | 18525.7 | 2822.7 | 1.0 | -0.663 | 0.008 | 2.714 | HCC1806 QL-VIII-58 0 2 |
| HCC1806 | QL-VIII-58 | 3 | 72 | 0.001 | 14551.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.010 | 2.697 | HCC1806 QL-VIII-58 0 3 |
| HCC1806 | QL-VIII-58 | 3 | 72 | 0.001 | 13237.0 | 14413.7 | 2222.1 | -3.0 | 0.938 | 0.918 | 2.697 | HCC1806 QL-VIII-58 0 3 |
| HCC1806 | QL-VIII-58 | 3 | 72 | 0.001 | 14640.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.020 | 2.697 | HCC1806 QL-VIII-58 0 3 |
| HCC1806 | QL-VIII-58 | 3 | 72 | 0.001 | 13724.0 | 14413.7 | 2222.1 | -3.0 | 0.964 | 0.952 | 2.697 | HCC1806 QL-VIII-58 0 3 |
| HCC1806 | QL-VIII-58 | 3 | 72 | 0.0032 | 14126.0 | 14413.7 | 2222.1 | -2.49 | 0.985 | 0.980 | 2.697 | HCC1806 QL-VIII-58 0 3 |