Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-47 | 1 | 72 | 0.01 | 7801.0 | 7580.8 | 2503.8 | -2.0 | 1.040 | 1.030 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0316 | 6916.0 | 7580.8 | 2503.8 | -1.5 | 0.888 | 0.912 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0316 | 7510.0 | 7580.8 | 2503.8 | -1.5 | 0.988 | 0.991 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0316 | 7877.0 | 7580.8 | 2503.8 | -1.5 | 1.050 | 1.040 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0316 | 7719.0 | 7580.8 | 2503.8 | -1.5 | 1.020 | 1.020 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.1 | 7256.0 | 7580.8 | 2503.8 | -1.0 | 0.946 | 0.957 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.1 | 7270.0 | 7580.8 | 2503.8 | -1.0 | 0.948 | 0.959 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.1 | 7887.0 | 7580.8 | 2503.8 | -1.0 | 1.050 | 1.040 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.1 | 7988.0 | 7580.8 | 2503.8 | -1.0 | 1.070 | 1.050 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.3162 | 6997.0 | 7580.8 | 2503.8 | -0.5 | 0.902 | 0.923 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.3162 | 7074.0 | 7580.8 | 2503.8 | -0.5 | 0.915 | 0.933 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.3162 | 6567.0 | 7580.8 | 2503.8 | -0.5 | 0.828 | 0.866 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.3162 | 7533.0 | 7580.8 | 2503.8 | -0.5 | 0.992 | 0.994 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 1.0 | 3819.0 | 7580.8 | 2503.8 | 0.0 | 0.302 | 0.504 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 1.0 | 3948.0 | 7580.8 | 2503.8 | 0.0 | 0.330 | 0.521 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 1.0 | 3338.0 | 7580.8 | 2503.8 | 0.0 | 0.197 | 0.440 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 1.0 | 3554.0 | 7580.8 | 2503.8 | 0.0 | 0.245 | 0.469 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 3.1623 | 513.0 | 7580.8 | 2503.8 | 0.5 | -0.629 | 0.068 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 3.1623 | 518.0 | 7580.8 | 2503.8 | 0.5 | -0.627 | 0.068 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 3.1623 | 641.0 | 7580.8 | 2503.8 | 0.5 | -0.574 | 0.085 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 3.1623 | 637.0 | 7580.8 | 2503.8 | 0.5 | -0.575 | 0.084 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 10.0 | 186.0 | 7580.8 | 2503.8 | 1.0 | -0.803 | 0.025 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 10.0 | 228.0 | 7580.8 | 2503.8 | 1.0 | -0.777 | 0.030 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 10.0 | 209.0 | 7580.8 | 2503.8 | 1.0 | -0.789 | 0.028 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 10.0 | 113.0 | 7580.8 | 2503.8 | 1.0 | -0.856 | 0.015 | 1.598 | HCC70 QL-XII-47 0 1 |