Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-108 | 3 | 72 | 0.3162 | 5393.0 | 6533.6 | 1943.1 | -0.5 | 0.792 | 0.825 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.3162 | 5477.0 | 6533.6 | 1943.1 | -0.5 | 0.808 | 0.838 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 1.0 | 4650.0 | 6533.6 | 1943.1 | 0.0 | 0.647 | 0.712 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 1.0 | 4089.0 | 6533.6 | 1943.1 | 0.0 | 0.530 | 0.626 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 1.0 | 4473.0 | 6533.6 | 1943.1 | 0.0 | 0.611 | 0.685 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 1.0 | 4296.0 | 6533.6 | 1943.1 | 0.0 | 0.574 | 0.658 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 3.1623 | 3277.0 | 6533.6 | 1943.1 | 0.5 | 0.348 | 0.502 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 3.1623 | 3490.0 | 6533.6 | 1943.1 | 0.5 | 0.398 | 0.534 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 3.1623 | 3495.0 | 6533.6 | 1943.1 | 0.5 | 0.399 | 0.535 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 3.1623 | 3472.0 | 6533.6 | 1943.1 | 0.5 | 0.393 | 0.531 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 10.0 | 2328.0 | 6533.6 | 1943.1 | 1.0 | 0.109 | 0.356 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 10.0 | 2504.0 | 6533.6 | 1943.1 | 1.0 | 0.156 | 0.383 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 10.0 | 2459.0 | 6533.6 | 1943.1 | 1.0 | 0.144 | 0.376 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 10.0 | 2634.0 | 6533.6 | 1943.1 | 1.0 | 0.190 | 0.403 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.001 | 7747.0 | 7580.8 | 2503.8 | -3.0 | 1.030 | 1.020 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.001 | 7255.0 | 7580.8 | 2503.8 | -3.0 | 0.946 | 0.957 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.001 | 7483.0 | 7580.8 | 2503.8 | -3.0 | 0.984 | 0.987 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.001 | 7193.0 | 7580.8 | 2503.8 | -3.0 | 0.935 | 0.949 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 7741.0 | 7580.8 | 2503.8 | -2.49 | 1.030 | 1.020 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 8198.0 | 7580.8 | 2503.8 | -2.49 | 1.100 | 1.080 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 8343.0 | 7580.8 | 2503.8 | -2.49 | 1.120 | 1.100 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.0032 | 8185.0 | 7580.8 | 2503.8 | -2.49 | 1.100 | 1.080 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.01 | 8013.0 | 7580.8 | 2503.8 | -2.0 | 1.070 | 1.060 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.01 | 7283.0 | 7580.8 | 2503.8 | -2.0 | 0.950 | 0.961 | 1.598 | HCC70 QL-XII-47 0 1 |
| HCC70 | QL-XII-47 | 1 | 72 | 0.01 | 7665.0 | 7580.8 | 2503.8 | -2.0 | 1.010 | 1.010 | 1.598 | HCC70 QL-XII-47 0 1 |