Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VIII-58 | 2 | 72 | 1.0 | 1243.0 | 7167.9 | 2409.0 | 0.0 | -0.343 | 0.173 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 1.0 | 1224.0 | 7167.9 | 2409.0 | 0.0 | -0.350 | 0.171 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 1.0 | 1136.0 | 7167.9 | 2409.0 | 0.0 | -0.380 | 0.158 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 1.0 | 1402.0 | 7167.9 | 2409.0 | 0.0 | -0.291 | 0.196 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 59.0 | 7167.9 | 2409.0 | 0.5 | -0.905 | 0.008 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 43.0 | 7167.9 | 2409.0 | 0.5 | -0.923 | 0.006 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 48.0 | 7167.9 | 2409.0 | 0.5 | -0.917 | 0.007 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 3.1623 | 27.0 | 7167.9 | 2409.0 | 0.5 | -0.942 | 0.004 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 10.0 | 14.0 | 7167.9 | 2409.0 | 1.0 | -0.962 | 0.002 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 10.0 | 5.0 | 7167.9 | 2409.0 | 1.0 | -0.980 | 0.001 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 10.0 | 5.0 | 7167.9 | 2409.0 | 1.0 | -0.980 | 0.001 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 10.0 | 11.0 | 7167.9 | 2409.0 | 1.0 | -0.967 | 0.002 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.001 | 6675.0 | 6533.6 | 1943.1 | -3.0 | 1.020 | 1.020 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.001 | 5676.0 | 6533.6 | 1943.1 | -3.0 | 0.845 | 0.869 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.001 | 5682.0 | 6533.6 | 1943.1 | -3.0 | 0.847 | 0.870 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.001 | 6022.0 | 6533.6 | 1943.1 | -3.0 | 0.909 | 0.922 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.0032 | 5520.0 | 6533.6 | 1943.1 | -2.49 | 0.816 | 0.845 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.0032 | 6122.0 | 6533.6 | 1943.1 | -2.49 | 0.927 | 0.937 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.0032 | 6475.0 | 6533.6 | 1943.1 | -2.49 | 0.990 | 0.991 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.0032 | 6403.0 | 6533.6 | 1943.1 | -2.49 | 0.977 | 0.980 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.01 | 5682.0 | 6533.6 | 1943.1 | -2.0 | 0.847 | 0.870 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.01 | 5388.0 | 6533.6 | 1943.1 | -2.0 | 0.791 | 0.825 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.01 | 5396.0 | 6533.6 | 1943.1 | -2.0 | 0.793 | 0.826 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.01 | 5371.0 | 6533.6 | 1943.1 | -2.0 | 0.788 | 0.822 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.0316 | 4502.0 | 6533.6 | 1943.1 | -1.5 | 0.617 | 0.689 | 1.750 | HCC70 QL-VIII-58 0 3 |