Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-108 | 2 | 72 | 10.0 | 2731.0 | 7167.9 | 2409.0 | 1.0 | 0.083 | 0.381 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 10.0 | 2698.0 | 7167.9 | 2409.0 | 1.0 | 0.075 | 0.376 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-108 | 2 | 72 | 10.0 | 2547.0 | 7167.9 | 2409.0 | 1.0 | 0.036 | 0.355 | 1.573 | HCC70 QL-XII-108 0 2 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.001 | 6070.0 | 6533.6 | 1943.1 | -3.0 | 0.918 | 0.929 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.001 | 6326.0 | 6533.6 | 1943.1 | -3.0 | 0.963 | 0.968 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.001 | 6483.0 | 6533.6 | 1943.1 | -3.0 | 0.991 | 0.992 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.001 | 6111.0 | 6533.6 | 1943.1 | -3.0 | 0.925 | 0.935 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.0032 | 6357.0 | 6533.6 | 1943.1 | -2.49 | 0.969 | 0.973 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.0032 | 6013.0 | 6533.6 | 1943.1 | -2.49 | 0.907 | 0.920 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.0032 | 6061.0 | 6533.6 | 1943.1 | -2.49 | 0.916 | 0.928 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.0032 | 5812.0 | 6533.6 | 1943.1 | -2.49 | 0.871 | 0.890 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.01 | 6993.0 | 6533.6 | 1943.1 | -2.0 | 1.080 | 1.070 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.01 | 5705.0 | 6533.6 | 1943.1 | -2.0 | 0.851 | 0.873 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.01 | 6353.0 | 6533.6 | 1943.1 | -2.0 | 0.968 | 0.972 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.01 | 6302.0 | 6533.6 | 1943.1 | -2.0 | 0.959 | 0.965 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.0316 | 6071.0 | 6533.6 | 1943.1 | -1.5 | 0.918 | 0.929 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.0316 | 5652.0 | 6533.6 | 1943.1 | -1.5 | 0.841 | 0.865 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.0316 | 6239.0 | 6533.6 | 1943.1 | -1.5 | 0.948 | 0.955 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.0316 | 6547.0 | 6533.6 | 1943.1 | -1.5 | 1.000 | 1.000 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.1 | 5945.0 | 6533.6 | 1943.1 | -1.0 | 0.895 | 0.910 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.1 | 6876.0 | 6533.6 | 1943.1 | -1.0 | 1.060 | 1.050 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.1 | 6597.0 | 6533.6 | 1943.1 | -1.0 | 1.010 | 1.010 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.1 | 6385.0 | 6533.6 | 1943.1 | -1.0 | 0.974 | 0.977 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.3162 | 5369.0 | 6533.6 | 1943.1 | -0.5 | 0.788 | 0.822 | 1.750 | HCC70 QL-XII-108 0 3 |
| HCC70 | QL-XII-108 | 3 | 72 | 0.3162 | 5122.0 | 6533.6 | 1943.1 | -0.5 | 0.740 | 0.784 | 1.750 | HCC70 QL-XII-108 0 3 |