Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VIII-58 | 1 | 72 | 10.0 | 8.0 | 7580.8 | 2503.8 | 1.0 | -0.973 | 0.001 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.001 | 7174.0 | 7167.9 | 2409.0 | -3.0 | 1.000 | 1.000 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.001 | 7711.0 | 7167.9 | 2409.0 | -3.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.001 | 6833.0 | 7167.9 | 2409.0 | -3.0 | 0.940 | 0.953 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.001 | 7425.0 | 7167.9 | 2409.0 | -3.0 | 1.050 | 1.040 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.0032 | 7193.0 | 7167.9 | 2409.0 | -2.49 | 1.000 | 1.000 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.0032 | 6911.0 | 7167.9 | 2409.0 | -2.49 | 0.954 | 0.964 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.0032 | 6484.0 | 7167.9 | 2409.0 | -2.49 | 0.876 | 0.905 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.0032 | 8043.0 | 7167.9 | 2409.0 | -2.49 | 1.150 | 1.120 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.01 | 6032.0 | 7167.9 | 2409.0 | -2.0 | 0.792 | 0.842 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.01 | 5797.0 | 7167.9 | 2409.0 | -2.0 | 0.748 | 0.809 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.01 | 6248.0 | 7167.9 | 2409.0 | -2.0 | 0.833 | 0.872 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.01 | 6179.0 | 7167.9 | 2409.0 | -2.0 | 0.820 | 0.862 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.0316 | 4598.0 | 7167.9 | 2409.0 | -1.5 | 0.508 | 0.641 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.0316 | 5102.0 | 7167.9 | 2409.0 | -1.5 | 0.611 | 0.712 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.0316 | 4710.0 | 7167.9 | 2409.0 | -1.5 | 0.531 | 0.657 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.0316 | 4600.0 | 7167.9 | 2409.0 | -1.5 | 0.509 | 0.642 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.1 | 3957.0 | 7167.9 | 2409.0 | -1.0 | 0.371 | 0.552 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.1 | 3870.0 | 7167.9 | 2409.0 | -1.0 | 0.352 | 0.540 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.1 | 3695.0 | 7167.9 | 2409.0 | -1.0 | 0.312 | 0.515 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.1 | 3924.0 | 7167.9 | 2409.0 | -1.0 | 0.364 | 0.547 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.3162 | 2963.0 | 7167.9 | 2409.0 | -0.5 | 0.141 | 0.413 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.3162 | 2766.0 | 7167.9 | 2409.0 | -0.5 | 0.092 | 0.386 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.3162 | 2921.0 | 7167.9 | 2409.0 | -0.5 | 0.130 | 0.408 | 1.573 | HCC70 QL-VIII-58 0 2 |
| HCC70 | QL-VIII-58 | 2 | 72 | 0.3162 | 2696.0 | 7167.9 | 2409.0 | -0.5 | 0.074 | 0.376 | 1.573 | HCC70 QL-VIII-58 0 2 |