Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VIII-58 | 1 | 72 | 0.01 | 6455.0 | 7580.8 | 2503.8 | -2.0 | 0.809 | 0.851 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.01 | 6661.0 | 7580.8 | 2503.8 | -2.0 | 0.845 | 0.879 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0316 | 5116.0 | 7580.8 | 2503.8 | -1.5 | 0.564 | 0.675 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0316 | 5232.0 | 7580.8 | 2503.8 | -1.5 | 0.586 | 0.690 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0316 | 5034.0 | 7580.8 | 2503.8 | -1.5 | 0.548 | 0.664 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0316 | 5057.0 | 7580.8 | 2503.8 | -1.5 | 0.552 | 0.667 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.1 | 4157.0 | 7580.8 | 2503.8 | -1.0 | 0.373 | 0.548 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.1 | 4119.0 | 7580.8 | 2503.8 | -1.0 | 0.365 | 0.543 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.1 | 4187.0 | 7580.8 | 2503.8 | -1.0 | 0.379 | 0.552 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.1 | 3946.0 | 7580.8 | 2503.8 | -1.0 | 0.329 | 0.521 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.3162 | 3159.0 | 7580.8 | 2503.8 | -0.5 | 0.157 | 0.417 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.3162 | 3348.0 | 7580.8 | 2503.8 | -0.5 | 0.199 | 0.442 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.3162 | 3131.0 | 7580.8 | 2503.8 | -0.5 | 0.150 | 0.413 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.3162 | 3139.0 | 7580.8 | 2503.8 | -0.5 | 0.152 | 0.414 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 1.0 | 1360.0 | 7580.8 | 2503.8 | 0.0 | -0.317 | 0.179 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 1.0 | 1469.0 | 7580.8 | 2503.8 | 0.0 | -0.284 | 0.194 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 1.0 | 1349.0 | 7580.8 | 2503.8 | 0.0 | -0.321 | 0.178 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 1.0 | 1619.0 | 7580.8 | 2503.8 | 0.0 | -0.239 | 0.214 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 48.0 | 7580.8 | 2503.8 | 0.5 | -0.916 | 0.006 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 64.0 | 7580.8 | 2503.8 | 0.5 | -0.899 | 0.008 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 54.0 | 7580.8 | 2503.8 | 0.5 | -0.909 | 0.007 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 3.1623 | 61.0 | 7580.8 | 2503.8 | 0.5 | -0.902 | 0.008 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 10.0 | 5.0 | 7580.8 | 2503.8 | 1.0 | -0.980 | 0.001 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 10.0 | 1.0 | 7580.8 | 2503.8 | 1.0 | -0.993 | 0.000 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 10.0 | 16.0 | 7580.8 | 2503.8 | 1.0 | -0.958 | 0.002 | 1.598 | HCC70 QL-VIII-58 0 1 |