Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VI-86 | 3 | 72 | 0.3162 | 3489.0 | 6533.6 | 1943.1 | -0.5 | 0.397 | 0.534 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.3162 | 4158.0 | 6533.6 | 1943.1 | -0.5 | 0.545 | 0.636 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 0.3162 | 3917.0 | 6533.6 | 1943.1 | -0.5 | 0.493 | 0.600 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 1.0 | 2628.0 | 6533.6 | 1943.1 | 0.0 | 0.188 | 0.402 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 1.0 | 2546.0 | 6533.6 | 1943.1 | 0.0 | 0.167 | 0.390 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 1.0 | 2583.0 | 6533.6 | 1943.1 | 0.0 | 0.177 | 0.395 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 1.0 | 2691.0 | 6533.6 | 1943.1 | 0.0 | 0.205 | 0.412 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 3.1623 | 917.0 | 6533.6 | 1943.1 | 0.5 | -0.349 | 0.140 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 3.1623 | 960.0 | 6533.6 | 1943.1 | 0.5 | -0.332 | 0.147 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 3.1623 | 829.0 | 6533.6 | 1943.1 | 0.5 | -0.385 | 0.127 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 3.1623 | 860.0 | 6533.6 | 1943.1 | 0.5 | -0.372 | 0.132 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 10.0 | 314.0 | 6533.6 | 1943.1 | 1.0 | -0.647 | 0.048 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 10.0 | 308.0 | 6533.6 | 1943.1 | 1.0 | -0.651 | 0.047 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 10.0 | 353.0 | 6533.6 | 1943.1 | 1.0 | -0.623 | 0.054 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VI-86 | 3 | 72 | 10.0 | 334.0 | 6533.6 | 1943.1 | 1.0 | -0.634 | 0.051 | 1.750 | HCC70 QL-VI-86 0 3 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.001 | 7499.0 | 7580.8 | 2503.8 | -3.0 | 0.986 | 0.989 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.001 | 7362.0 | 7580.8 | 2503.8 | -3.0 | 0.964 | 0.971 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.001 | 6963.0 | 7580.8 | 2503.8 | -3.0 | 0.896 | 0.919 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.001 | 7490.0 | 7580.8 | 2503.8 | -3.0 | 0.985 | 0.988 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0032 | 7254.0 | 7580.8 | 2503.8 | -2.49 | 0.946 | 0.957 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0032 | 7562.0 | 7580.8 | 2503.8 | -2.49 | 0.997 | 0.998 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0032 | 7250.0 | 7580.8 | 2503.8 | -2.49 | 0.945 | 0.956 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.0032 | 7694.0 | 7580.8 | 2503.8 | -2.49 | 1.020 | 1.010 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.01 | 6485.0 | 7580.8 | 2503.8 | -2.0 | 0.814 | 0.855 | 1.598 | HCC70 QL-VIII-58 0 1 |
| HCC70 | QL-VIII-58 | 1 | 72 | 0.01 | 6208.0 | 7580.8 | 2503.8 | -2.0 | 0.765 | 0.819 | 1.598 | HCC70 QL-VIII-58 0 1 |