Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-61 | 3 | 72 | 3.1623 | 5893.0 | 6533.6 | 1943.1 | 0.5 | 0.885 | 0.902 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 10.0 | 2414.0 | 6533.6 | 1943.1 | 1.0 | 0.132 | 0.369 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 10.0 | 2314.0 | 6533.6 | 1943.1 | 1.0 | 0.105 | 0.354 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 10.0 | 2503.0 | 6533.6 | 1943.1 | 1.0 | 0.156 | 0.383 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | QL-XII-61 | 3 | 72 | 10.0 | 2629.0 | 6533.6 | 1943.1 | 1.0 | 0.189 | 0.402 | 1.750 | HCC70 QL-XII-61 0 3 |
| HCC70 | Torin1 | 1 | 72 | 0.001 | 7483.0 | 7580.8 | 2503.8 | -3.0 | 0.984 | 0.987 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.001 | 6906.0 | 7580.8 | 2503.8 | -3.0 | 0.887 | 0.911 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.001 | 6608.0 | 7580.8 | 2503.8 | -3.0 | 0.835 | 0.872 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.001 | 8154.0 | 7580.8 | 2503.8 | -3.0 | 1.090 | 1.080 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0032 | 6630.0 | 7580.8 | 2503.8 | -2.49 | 0.839 | 0.875 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0032 | 6595.0 | 7580.8 | 2503.8 | -2.49 | 0.833 | 0.870 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0032 | 7902.0 | 7580.8 | 2503.8 | -2.49 | 1.050 | 1.040 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0032 | 7176.0 | 7580.8 | 2503.8 | -2.49 | 0.933 | 0.947 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.01 | 6181.0 | 7580.8 | 2503.8 | -2.0 | 0.760 | 0.815 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.01 | 6415.0 | 7580.8 | 2503.8 | -2.0 | 0.802 | 0.846 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.01 | 6063.0 | 7580.8 | 2503.8 | -2.0 | 0.739 | 0.800 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.01 | 6522.0 | 7580.8 | 2503.8 | -2.0 | 0.820 | 0.860 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0316 | 5070.0 | 7580.8 | 2503.8 | -1.5 | 0.555 | 0.669 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0316 | 5512.0 | 7580.8 | 2503.8 | -1.5 | 0.638 | 0.727 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0316 | 4961.0 | 7580.8 | 2503.8 | -1.5 | 0.534 | 0.654 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.0316 | 5704.0 | 7580.8 | 2503.8 | -1.5 | 0.674 | 0.752 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.1 | 4134.0 | 7580.8 | 2503.8 | -1.0 | 0.369 | 0.545 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.1 | 3858.0 | 7580.8 | 2503.8 | -1.0 | 0.311 | 0.509 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.1 | 4442.0 | 7580.8 | 2503.8 | -1.0 | 0.431 | 0.586 | 1.598 | HCC70 Torin1 0 1 |
| HCC70 | Torin1 | 1 | 72 | 0.1 | 4169.0 | 7580.8 | 2503.8 | -1.0 | 0.376 | 0.550 | 1.598 | HCC70 Torin1 0 1 |