Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin1 | 2 | 72 | 0.01 | 5740.0 | 7167.9 | 2409.0 | -2.0 | 0.737 | 0.801 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.01 | 5649.0 | 7167.9 | 2409.0 | -2.0 | 0.719 | 0.788 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.01 | 6292.0 | 7167.9 | 2409.0 | -2.0 | 0.841 | 0.878 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.0316 | 4271.0 | 7167.9 | 2409.0 | -1.5 | 0.439 | 0.596 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.0316 | 4694.0 | 7167.9 | 2409.0 | -1.5 | 0.528 | 0.655 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.0316 | 3855.0 | 7167.9 | 2409.0 | -1.5 | 0.348 | 0.538 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.0316 | 4819.0 | 7167.9 | 2409.0 | -1.5 | 0.554 | 0.672 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.1 | 3703.0 | 7167.9 | 2409.0 | -1.0 | 0.314 | 0.517 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.1 | 3503.0 | 7167.9 | 2409.0 | -1.0 | 0.269 | 0.489 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.1 | 3886.0 | 7167.9 | 2409.0 | -1.0 | 0.355 | 0.542 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.1 | 3385.0 | 7167.9 | 2409.0 | -1.0 | 0.241 | 0.472 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.3162 | 2892.0 | 7167.9 | 2409.0 | -0.5 | 0.123 | 0.403 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.3162 | 2619.0 | 7167.9 | 2409.0 | -0.5 | 0.055 | 0.365 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.3162 | 3087.0 | 7167.9 | 2409.0 | -0.5 | 0.171 | 0.431 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 0.3162 | 2919.0 | 7167.9 | 2409.0 | -0.5 | 0.130 | 0.407 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 1.0 | 2479.0 | 7167.9 | 2409.0 | 0.0 | 0.018 | 0.346 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 1.0 | 2587.0 | 7167.9 | 2409.0 | 0.0 | 0.046 | 0.361 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 1.0 | 2714.0 | 7167.9 | 2409.0 | 0.0 | 0.079 | 0.379 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 1.0 | 2403.0 | 7167.9 | 2409.0 | 0.0 | -0.002 | 0.335 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 3.1623 | 2276.0 | 7167.9 | 2409.0 | 0.5 | -0.036 | 0.318 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 3.1623 | 2190.0 | 7167.9 | 2409.0 | 0.5 | -0.059 | 0.306 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 3.1623 | 2271.0 | 7167.9 | 2409.0 | 0.5 | -0.037 | 0.317 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 3.1623 | 1892.0 | 7167.9 | 2409.0 | 0.5 | -0.142 | 0.264 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 10.0 | 1445.0 | 7167.9 | 2409.0 | 1.0 | -0.277 | 0.202 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 10.0 | 1345.0 | 7167.9 | 2409.0 | 1.0 | -0.310 | 0.188 | 1.573 | HCC70 Torin1 0 2 |