Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-VIII-58 | 3 | 72 | 0.0316 | 4676.0 | 6533.6 | 1943.1 | -1.5 | 0.652 | 0.716 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.0316 | 4294.0 | 6533.6 | 1943.1 | -1.5 | 0.573 | 0.657 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.0316 | 4464.0 | 6533.6 | 1943.1 | -1.5 | 0.609 | 0.683 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.1 | 3334.0 | 6533.6 | 1943.1 | -1.0 | 0.362 | 0.510 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.1 | 3379.0 | 6533.6 | 1943.1 | -1.0 | 0.372 | 0.517 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.1 | 3408.0 | 6533.6 | 1943.1 | -1.0 | 0.379 | 0.522 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.1 | 3343.0 | 6533.6 | 1943.1 | -1.0 | 0.364 | 0.512 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.3162 | 2569.0 | 6533.6 | 1943.1 | -0.5 | 0.173 | 0.393 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.3162 | 2633.0 | 6533.6 | 1943.1 | -0.5 | 0.190 | 0.403 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.3162 | 2625.0 | 6533.6 | 1943.1 | -0.5 | 0.188 | 0.402 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 0.3162 | 2696.0 | 6533.6 | 1943.1 | -0.5 | 0.206 | 0.413 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 1.0 | 1269.0 | 6533.6 | 1943.1 | 0.0 | -0.216 | 0.194 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 1.0 | 1226.0 | 6533.6 | 1943.1 | 0.0 | -0.231 | 0.188 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 1.0 | 1153.0 | 6533.6 | 1943.1 | 0.0 | -0.258 | 0.176 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 1.0 | 1373.0 | 6533.6 | 1943.1 | 0.0 | -0.180 | 0.210 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 98.0 | 6533.6 | 1943.1 | 0.5 | -0.819 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 96.0 | 6533.6 | 1943.1 | 0.5 | -0.821 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 116.0 | 6533.6 | 1943.1 | 0.5 | -0.800 | 0.018 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 3.1623 | 98.0 | 6533.6 | 1943.1 | 0.5 | -0.819 | 0.015 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 10.0 | 14.0 | 6533.6 | 1943.1 | 1.0 | -0.940 | 0.002 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 10.0 | 13.0 | 6533.6 | 1943.1 | 1.0 | -0.943 | 0.002 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 10.0 | 13.0 | 6533.6 | 1943.1 | 1.0 | -0.943 | 0.002 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-VIII-58 | 3 | 72 | 10.0 | 14.0 | 6533.6 | 1943.1 | 1.0 | -0.940 | 0.002 | 1.750 | HCC70 QL-VIII-58 0 3 |
| HCC70 | QL-X-138 | 1 | 72 | 0.001 | 7629.0 | 7580.8 | 2503.8 | -3.0 | 1.010 | 1.010 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 0.001 | 7447.0 | 7580.8 | 2503.8 | -3.0 | 0.978 | 0.982 | 1.598 | HCC70 QL-X-138 0 1 |