Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)

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Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC1806 KIN001-244 1 72
0.001
 11912.3 11660.3 1742.8
-3.0
 1.020 1.020 2.742
HCC1806 KIN001-244 0 1 72
HCC1806 KIN001-244 1 72
0.0032
 11082.0 11660.3 1742.8
-2.49
 0.963 0.950 2.742
HCC1806 KIN001-244 0 1 72
HCC1806 KIN001-244 1 72
0.01
 10733.5 11660.3 1742.8
-2.0
 0.940 0.921 2.742
HCC1806 KIN001-244 0 1 72
HCC1806 KIN001-244 1 72
0.032
 10972.3 11660.3 1742.8
-1.49
 0.956 0.941 2.742
HCC1806 KIN001-244 0 1 72
HCC1806 KIN001-244 1 72
0.1
 11622.0 11660.3 1742.8
-1.0
 0.998 0.997 2.742
HCC1806 KIN001-244 0 1 72
HCC1806 KIN001-244 1 72
0.32
 11461.0 11660.3 1742.8
-0.495
 0.987 0.983 2.742
HCC1806 KIN001-244 0 1 72
HCC1806 KIN001-244 1 72
1.0
 11475.5 11660.3 1742.8
0.0
 0.988 0.984 2.742
HCC1806 KIN001-244 0 1 72
HCC1806 KIN001-244 1 72
3.2
 11439.0 11660.3 1742.8
0.505
 0.986 0.981 2.742
HCC1806 KIN001-244 0 1 72
HCC1806 MK2206 1 72
0.001
 11458.3 11692.5 1742.8
-3.0
 0.985 0.980 2.746
HCC1806 MK2206 0 1 72
HCC1806 MK2206 1 72
0.0032
 11472.3 11692.5 1742.8
-2.49
 0.986 0.981 2.746
HCC1806 MK2206 0 1 72
HCC1806 MK2206 1 72
0.01
 11541.0 11692.5 1742.8
-2.0
 0.991 0.987 2.746
HCC1806 MK2206 0 1 72
HCC1806 MK2206 1 72
0.032
 11428.3 11692.5 1742.8
-1.49
 0.983 0.977 2.746
HCC1806 MK2206 0 1 72
HCC1806 MK2206 1 72
0.1
 11113.3 11692.5 1742.8
-1.0
 0.963 0.950 2.746
HCC1806 MK2206 0 1 72
HCC1806 MK2206 1 72
0.32
 10467.5 11692.5 1742.8
-0.495
 0.921 0.895 2.746
HCC1806 MK2206 0 1 72
HCC1806 MK2206 1 72
1.0
 10180.5 11692.5 1742.8
0.0
 0.902 0.871 2.746
HCC1806 MK2206 0 1 72
HCC1806 MK2206 1 72
3.2
 8994.8 11692.5 1742.8
0.505
 0.818 0.769 2.746
HCC1806 MK2206 0 1 72
HCC1806 PI103 1 72
0.001
 10973.0 11113.3 1742.8
-3.0
 0.991 0.987 2.673
HCC1806 PI103 0 1 72
HCC1806 PI103 1 72
0.0032
 11168.3 11113.3 1742.8
-2.49
 1.000 1.000 2.673
HCC1806 PI103 0 1 72
HCC1806 PI103 1 72
0.01
 11663.8 11113.3 1742.8
-2.0
 1.040 1.050 2.673
HCC1806 PI103 0 1 72
HCC1806 PI103 1 72
0.032
 11750.3 11113.3 1742.8
-1.49
 1.040 1.060 2.673
HCC1806 PI103 0 1 72
HCC1806 PI103 1 72
0.1
 10951.8 11113.3 1742.8
-1.0
 0.989 0.985 2.673
HCC1806 PI103 0 1 72
HCC1806 PI103 1 72
0.32
 10874.3 11113.3 1742.8
-0.495
 0.984 0.978 2.673
HCC1806 PI103 0 1 72
HCC1806 PI103 1 72
1.0
 10453.3 11113.3 1742.8
0.0
 0.955 0.941 2.673
HCC1806 PI103 0 1 72
HCC1806 PI103 1 72
3.2
 9624.3 11113.3 1742.8
0.505
 0.895 0.866 2.673
HCC1806 PI103 0 1 72
HCC1806 PIK-93 1 72
0.001
 11663.0 11752.8 1742.8
-3.0
 0.994 0.992 2.753
HCC1806 PIK93 0 1 72