Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)

 Full screen view
Filter results: >>>>
Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
Hs 578T Dactolisib 2 72
0.1
 1055.0 3555.0 624.7
-1.0
 0.232 0.297 2.509
Hs578T BEZ235 2
Hs 578T Dactolisib 2 72
0.32
 829.8 3555.0 624.7
-0.495
 0.120 0.233 2.509
Hs578T BEZ235 2
Hs 578T Dactolisib 2 72
1.0
 728.5 3555.0 624.7
0.0
 0.063 0.205 2.509
Hs578T BEZ235 2
Hs 578T Dactolisib 2 72
3.2
 532.5 3555.0 624.7
0.505
 -0.062 0.150 2.509
Hs578T BEZ235 2
Hs 578T Buparlisib 2 72
0.001
 3710.0 3566.8 624.7
-3.0
 1.030 1.040 2.513
Hs578T BKM120 2
Hs 578T Buparlisib 2 72
0.0032
 3593.8 3566.8 624.7
-2.49
 1.010 1.010 2.513
Hs578T BKM120 2
Hs 578T Buparlisib 2 72
0.01
 3527.8 3566.8 624.7
-2.0
 0.991 0.989 2.513
Hs578T BKM120 2
Hs 578T Buparlisib 2 72
0.032
 3475.3 3566.8 624.7
-1.49
 0.979 0.974 2.513
Hs578T BKM120 2
Hs 578T Buparlisib 2 72
0.1
 3150.3 3566.8 624.7
-1.0
 0.904 0.883 2.513
Hs578T BKM120 2
Hs 578T Buparlisib 2 72
0.32
 2526.5 3566.8 624.7
-0.495
 0.744 0.708 2.513
Hs578T BKM120 2
Hs 578T Buparlisib 2 72
1.0
 1255.0 3566.8 624.7
0.0
 0.320 0.352 2.513
Hs578T BKM120 2
Hs 578T Buparlisib 2 72
3.2
 158.8 3566.8 624.7
0.505
 -0.420 0.045 2.513
Hs578T BKM120 2
Hs 578T BX-912 2 72
0.001
 3521.3 3632.8 624.7
-3.0
 0.976 0.969 2.540
Hs578T BX912 2
Hs 578T BX-912 2 72
0.0032
 3582.0 3632.8 624.7
-2.49
 0.989 0.986 2.540
Hs578T BX912 2
Hs 578T BX-912 2 72
0.01
 3561.8 3632.8 624.7
-2.0
 0.985 0.980 2.540
Hs578T BX912 2
Hs 578T BX-912 2 72
0.032
 3564.0 3632.8 624.7
-1.49
 0.985 0.981 2.540
Hs578T BX912 2
Hs 578T BX-912 2 72
0.1
 3390.3 3632.8 624.7
-1.0
 0.946 0.933 2.540
Hs578T BX912 2
Hs 578T BX-912 2 72
0.32
 3091.5 3632.8 624.7
-0.495
 0.877 0.851 2.540
Hs578T BX912 2
Hs 578T BX-912 2 72
1.0
 1822.8 3632.8 624.7
0.0
 0.524 0.502 2.540
Hs578T BX912 2
Hs 578T BX-912 2 72
3.2
 595.0 3632.8 624.7
0.505
 -0.019 0.164 2.540
Hs578T BX912 2
Hs 578T Alpelisib 2 72
0.001
 2972.3 3566.3 624.7
-3.0
 0.860 0.833 2.513
Hs578T BYL719 2
Hs 578T Alpelisib 2 72
0.0032
 2946.5 3566.3 624.7
-2.49
 0.854 0.826 2.513
Hs578T BYL719 2
Hs 578T Alpelisib 2 72
0.01
 3462.0 3566.3 624.7
-2.0
 0.977 0.971 2.513
Hs578T BYL719 2
Hs 578T Alpelisib 2 72
0.032
 3302.8 3566.3 624.7
-1.49
 0.940 0.926 2.513
Hs578T BYL719 2
Hs 578T Alpelisib 2 72
0.1
 3269.8 3566.3 624.7
-1.0
 0.932 0.917 2.513
Hs578T BYL719 2