Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | BX-912 | 1 | 72 | 0.32 | 2901.5 | 3493.8 | 873.1 | -0.495 | 0.823 | 0.830 | 2.001 | Hs578T BX912 1 |
| Hs 578T | BX-912 | 1 | 72 | 1.0 | 1620.3 | 3493.8 | 873.1 | 0.0 | 0.362 | 0.464 | 2.001 | Hs578T BX912 1 |
| Hs 578T | BX-912 | 1 | 72 | 3.2 | 555.8 | 3493.8 | 873.1 | 0.505 | -0.202 | 0.159 | 2.001 | Hs578T BX912 1 |
| Hs 578T | Alpelisib | 1 | 72 | 0.001 | 3568.3 | 3736.0 | 873.1 | -3.0 | 0.957 | 0.955 | 2.097 | Hs578T BYL719 1 |
| Hs 578T | Alpelisib | 1 | 72 | 0.0032 | 3187.3 | 3736.0 | 873.1 | -2.49 | 0.854 | 0.853 | 2.097 | Hs578T BYL719 1 |
| Hs 578T | Alpelisib | 1 | 72 | 0.01 | 3514.8 | 3736.0 | 873.1 | -2.0 | 0.943 | 0.941 | 2.097 | Hs578T BYL719 1 |
| Hs 578T | Alpelisib | 1 | 72 | 0.032 | 3370.0 | 3736.0 | 873.1 | -1.49 | 0.904 | 0.902 | 2.097 | Hs578T BYL719 1 |
| Hs 578T | Alpelisib | 1 | 72 | 0.1 | 3106.5 | 3736.0 | 873.1 | -1.0 | 0.832 | 0.832 | 2.097 | Hs578T BYL719 1 |
| Hs 578T | Alpelisib | 1 | 72 | 0.32 | 2729.8 | 3736.0 | 873.1 | -0.495 | 0.722 | 0.731 | 2.097 | Hs578T BYL719 1 |
| Hs 578T | Alpelisib | 1 | 72 | 1.0 | 2366.8 | 3736.0 | 873.1 | 0.0 | 0.609 | 0.633 | 2.097 | Hs578T BYL719 1 |
| Hs 578T | Alpelisib | 1 | 72 | 3.2 | 1899.5 | 3736.0 | 873.1 | 0.505 | 0.449 | 0.508 | 2.097 | Hs578T BYL719 1 |
| Hs 578T | CAL-101 | 1 | 72 | 0.001 | 3520.5 | 3615.0 | 873.1 | -3.0 | 0.974 | 0.974 | 2.050 | Hs578T CAL101 1 |
| Hs 578T | CAL-101 | 1 | 72 | 0.0032 | 3484.3 | 3615.0 | 873.1 | -2.49 | 0.964 | 0.964 | 2.050 | Hs578T CAL101 1 |
| Hs 578T | CAL-101 | 1 | 72 | 0.01 | 3512.3 | 3615.0 | 873.1 | -2.0 | 0.972 | 0.972 | 2.050 | Hs578T CAL101 1 |
| Hs 578T | CAL-101 | 1 | 72 | 0.032 | 3470.0 | 3615.0 | 873.1 | -1.49 | 0.960 | 0.960 | 2.050 | Hs578T CAL101 1 |
| Hs 578T | CAL-101 | 1 | 72 | 0.1 | 3506.5 | 3615.0 | 873.1 | -1.0 | 0.970 | 0.970 | 2.050 | Hs578T CAL101 1 |
| Hs 578T | CAL-101 | 1 | 72 | 0.32 | 3386.8 | 3615.0 | 873.1 | -0.495 | 0.937 | 0.937 | 2.050 | Hs578T CAL101 1 |
| Hs 578T | CAL-101 | 1 | 72 | 1.0 | 2960.5 | 3615.0 | 873.1 | 0.0 | 0.814 | 0.819 | 2.050 | Hs578T CAL101 1 |
| Hs 578T | CAL-101 | 1 | 72 | 3.2 | 2654.0 | 3615.0 | 873.1 | 0.505 | 0.720 | 0.734 | 2.050 | Hs578T CAL101 1 |
| Hs 578T | Everolimus | 1 | 72 | 0.001 | 2723.5 | 3566.8 | 873.1 | -3.0 | 0.751 | 0.764 | 2.030 | Hs578T Everolimus 1 |
| Hs 578T | Everolimus | 1 | 72 | 0.0032 | 2551.3 | 3566.8 | 873.1 | -2.49 | 0.696 | 0.715 | 2.030 | Hs578T Everolimus 1 |
| Hs 578T | Everolimus | 1 | 72 | 0.01 | 2623.5 | 3566.8 | 873.1 | -2.0 | 0.719 | 0.736 | 2.030 | Hs578T Everolimus 1 |
| Hs 578T | Everolimus | 1 | 72 | 0.032 | 2527.8 | 3566.8 | 873.1 | -1.49 | 0.688 | 0.709 | 2.030 | Hs578T Everolimus 1 |
| Hs 578T | Everolimus | 1 | 72 | 0.1 | 2494.8 | 3566.8 | 873.1 | -1.0 | 0.677 | 0.699 | 2.030 | Hs578T Everolimus 1 |
| Hs 578T | Everolimus | 1 | 72 | 0.32 | 2471.3 | 3566.8 | 873.1 | -0.495 | 0.669 | 0.693 | 2.030 | Hs578T Everolimus 1 |