LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20362)

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Cell Small Molecule Timepoint GR50 GRmax GR_AOC GEC50 GRinf h_GR r2_GR pval_GR
MCF10A-GM_4
 Alpelisib 72
14.7321
 0.5350 0.1188 119.95795 -1.0000 0.5239 0.9638
1.11022302463e-16
MCF10A-GM_8
 Alpelisib 72
17.8393
 0.5275 0.0998 138.06189 -1.0000 0.5369 0.9510
3.88578058619e-15
MCF10A-GM_6
 Alpelisib 72
13.6674
 0.5343 0.1095 92.70681 -1.0000 0.5739 0.9770
1.11022302463e-16
MCF10A-GM_1
 Alpelisib 72
16.8047
 0.5253 0.1124 16.38007 0.0074 0.5799 0.9822
1.11022302463e-16
MCF10A-GM_4
 Dasatinib 72
0.5549
 -0.0532 0.3996 1.34090 -0.3371 0.5842 0.9860
1.11022302463e-16
MCF10A-GM_8
 Dasatinib 72
0.7613
 -0.0880 0.3632 2.43718 -0.4869 0.5844 0.9823
1.11022302463e-16
MCF10A-GM_3
 Alpelisib 72
12.9167
 0.5328 0.1116 73.65654 -0.8864 0.5858 0.9876
1.11022302463e-16
MCF10A-GM_5
 Alpelisib 72
12.6322
 0.5207 0.1108 81.30890 -1.0000 0.5900 0.9846
1.11022302463e-16
MCF10A-GM_5
 Dasatinib 72
0.6795
 -0.0849 0.3753 1.79909 -0.3886 0.5905 0.9862
1.11022302463e-16
MCF10A-GM_1
 Palbociclib 72
0.5322
 0.1211 0.3355 0.54895 -0.0094 0.5976 0.9648
1.11022302463e-16
MCF10A-GM_7
 Dasatinib 72
0.7106
 -0.0667 0.3612 1.65872 -0.3419 0.6146 0.9852
1.11022302463e-16
MCF10A-GM_5
 Palbociclib 72
1.3443
 0.1381 0.2526 0.87951 0.1153 0.6180 0.9252
8.43769498715e-15
MCF10A-GM_4
 Palbociclib 72
1.2786
 0.1204 0.2510 1.13395 0.0360 0.6224 0.9308
3.10862446895e-15
MCF10A-GM_6
 Dasatinib 72
0.6238
 -0.0558 0.3803 1.40075 -0.3286 0.6244 0.9838
1.11022302463e-16
MCF10A-GM_2
 Dasatinib 72
0.5372
 -0.0593 0.3896 1.05022 -0.2667 0.6377 0.9780
1.11022302463e-16
MCF10A-GM_3
 Palbociclib 72
0.8312
 0.1260 0.2902 0.65210 0.0722 0.6423 0.9643
1.11022302463e-16
MCF10A-GM_9
 Dasatinib 72
0.8384
 -0.0654 0.3421 1.94935 -0.3664 0.6515 0.9807
1.11022302463e-16
MCF10A-GM_3
 Dasatinib 72
0.5827
 -0.0566 0.3862 1.12437 -0.2687 0.6544 0.9878
1.11022302463e-16
MCF10A-GM_6
 Palbociclib 72
1.6855
 0.1558 0.2242 1.17921 0.1046 0.6573 0.9371
9.99200722163e-16
MCF10A-GM_1
 Dasatinib 72
0.4799
 -0.0596 0.4113 0.84280 -0.2282 0.6676 0.9832
1.11022302463e-16
MCF10A-GM_9
 Alpelisib 72
40.5553
 0.6142 0.0999 7.33308 0.3417 0.6724 0.9520
1.43218770177e-14
MCF10A-GM_2
 Palbociclib 72
0.6209
 0.1517 0.3099 0.48785 0.0759 0.6830 0.9438
2.22044604925e-16
MCF10A-GM_2
 Alpelisib 72
14.1515
 0.5378 0.1207 7.55411 0.1758 0.6903 0.9747
1.11022302463e-16
MCF10A-GM_8
 Palbociclib 72
2.0079
 0.2005 0.1953 0.67438 0.2875 0.7841 0.9289
4.4408920985e-15
MCF10A-GM_7
 Palbociclib 72
1.4192
 0.1315 0.1975 0.46657 0.3096 0.8680 0.8643
1.44168010863e-11
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