LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20362)
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| Cell | Small Molecule | Timepoint | GR50 | GRmax | GR_AOC | GEC50 | GRinf | h_GR | r2_GR | pval_GR |
|---|---|---|---|---|---|---|---|---|---|---|
MCF10A-GM_9 | Taxol | 72 | 0.0044 | -0.2005 | 0.6800 | 0.00529 | -0.1770 | 1.6339 | 0.9825 | 1.11022302463e-15 |
MCF10A-GM_1 | Taxol | 72 | 0.0031 | -0.1839 | 0.7432 | 0.00360 | -0.1412 | 1.8163 | 0.9877 | 1.11022302463e-16 |
MCF10A-GM_3 | Taxol | 72 | 0.0031 | -0.1829 | 0.7472 | 0.00355 | -0.1448 | 1.8150 | 0.9882 | 1.11022302463e-16 |
MCF10A-GM_5 | Taxol | 72 | 0.0035 | -0.1747 | 0.7341 | 0.00408 | -0.1521 | 1.6592 | 0.9847 | 1.11022302463e-16 |
MCF10A-GM_8 | Taxol | 72 | 0.0043 | -0.1715 | 0.7088 | 0.00525 | -0.1769 | 1.5821 | 0.9820 | 1.11022302463e-16 |
MCF10A-GM_2 | Taxol | 72 | 0.0032 | -0.1684 | 0.7416 | 0.00371 | -0.1410 | 1.6859 | 0.9894 | 1.11022302463e-16 |
MCF10A-GM_4 | Taxol | 72 | 0.0035 | -0.1612 | 0.7179 | 0.00406 | -0.1470 | 1.7773 | 0.9895 | 1.11022302463e-16 |
MCF10A-GM_6 | Taxol | 72 | 0.0036 | -0.1585 | 0.7040 | 0.00409 | -0.1386 | 1.7468 | 0.9850 | 1.11022302463e-16 |
MCF10A-GM_7 | Taxol | 72 | 0.0042 | -0.1484 | 0.7164 | 0.00501 | -0.1660 | 1.6732 | 0.9838 | 1.11022302463e-16 |
MCF10A-GM_8 | Dasatinib | 72 | 0.7613 | -0.0880 | 0.3632 | 2.43718 | -0.4869 | 0.5844 | 0.9823 | 1.11022302463e-16 |
MCF10A-GM_5 | Dasatinib | 72 | 0.6795 | -0.0849 | 0.3753 | 1.79909 | -0.3886 | 0.5905 | 0.9862 | 1.11022302463e-16 |
MCF10A-GM_7 | Dasatinib | 72 | 0.7106 | -0.0667 | 0.3612 | 1.65872 | -0.3419 | 0.6146 | 0.9852 | 1.11022302463e-16 |
MCF10A-GM_9 | Dasatinib | 72 | 0.8384 | -0.0654 | 0.3421 | 1.94935 | -0.3664 | 0.6515 | 0.9807 | 1.11022302463e-16 |
MCF10A-GM_1 | Dasatinib | 72 | 0.4799 | -0.0596 | 0.4113 | 0.84280 | -0.2282 | 0.6676 | 0.9832 | 1.11022302463e-16 |
MCF10A-GM_2 | Dasatinib | 72 | 0.5372 | -0.0593 | 0.3896 | 1.05022 | -0.2667 | 0.6377 | 0.9780 | 1.11022302463e-16 |
MCF10A-GM_3 | Dasatinib | 72 | 0.5827 | -0.0566 | 0.3862 | 1.12437 | -0.2687 | 0.6544 | 0.9878 | 1.11022302463e-16 |
MCF10A-GM_6 | Dasatinib | 72 | 0.6238 | -0.0558 | 0.3803 | 1.40075 | -0.3286 | 0.6244 | 0.9838 | 1.11022302463e-16 |
MCF10A-GM_4 | Dasatinib | 72 | 0.5549 | -0.0532 | 0.3996 | 1.34090 | -0.3371 | 0.5842 | 0.9860 | 1.11022302463e-16 |
MCF10A-GM_2 | Etoposide | 72 | 0.271 | -0.0003 | 0.4708 | 0.28492 | -0.0360 | 1.3828 | 0.9925 | 1.11022302463e-16 |
MCF10A-GM_5 | Etoposide | 72 | 0.2926 | 0.0114 | 0.4454 | 0.29626 | -0.0089 | 1.4036 | 0.9925 | 1.11022302463e-16 |
MCF10A-GM_4 | Etoposide | 72 | 0.2814 | 0.0170 | 0.4542 | 0.28897 | -0.0173 | 1.2781 | 0.9882 | 1.11022302463e-16 |
MCF10A-GM_7 | Etoposide | 72 | 0.3136 | 0.0260 | 0.4219 | 0.30971 | 0.0089 | 1.4497 | 0.9861 | 1.11022302463e-16 |
MCF10A-GM_1 | Etoposide | 72 | 0.2477 | 0.0271 | 0.4660 | 0.24946 | -0.0050 | 1.4185 | 0.9937 | 1.11022302463e-16 |
MCF10A-GM_3 | Etoposide | 72 | 0.2684 | 0.0290 | 0.4530 | 0.26650 | 0.0050 | 1.4125 | 0.9928 | 1.11022302463e-16 |
MCF10A-GM_8 | Etoposide | 72 | 0.3332 | 0.0318 | 0.4204 | 0.33520 | -0.0040 | 1.3426 | 0.9936 | 1.11022302463e-16 |