LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vorinostat | 180619_MC_12 | 687 | 0.2456 | 160 | 48 | 11 | 14 | Vorinostat | 9.98 | treatment | 72 | 2 | MCF10A-GM_8 | 208 | 0.2324 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.20933 | 0.0171 |
| Vorinostat | 180619_MC_12 | 746 | 0.1278 | 68 | 36 | 12 | 16 | Vorinostat | 9.98 | treatment | 72 | 2 | MCF10A-GM_9 | 104 | 0.1224 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.09928 | 0.0356 |
| Alpelisib | 180622_MC_14 | 19796 | 0.0272 | 65 | 475 | 7 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 540 | 0.0266 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00249 | 1.0075 |
| Alpelisib | 180622_MC_14 | 19660 | 0.0281 | 71 | 483 | 8 | 11 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 554 | 0.0274 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00334 | 1.0040 |
| Alpelisib | 180622_MC_14 | 19332 | 0.0268 | 44 | 475 | 12 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_3 | 519 | 0.0261 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00208 | 0.9955 |
| Alpelisib | 180622_MC_15 | 19214 | 0.0209 | 55 | 347 | 3 | 13 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_4 | 402 | 0.0205 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00357 | 0.9924 |
| Alpelisib | 180622_MC_15 | 18632 | 0.0218 | 72 | 336 | 8 | 17 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_5 | 408 | 0.0214 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00264 | 0.9770 |
| Alpelisib | 180622_MC_15 | 19639 | 0.0219 | 51 | 381 | 13 | 15 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_6 | 432 | 0.0215 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00254 | 1.0035 |
| Alpelisib | 180622_MC_16 | 19799 | 0.0256 | 91 | 418 | 9 | 21 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_7 | 509 | 0.0251 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00100 | 1.0076 |
| Alpelisib | 180622_MC_16 | 19477 | 0.0318 | 143 | 480 | 11 | 6 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 623 | 0.0310 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00693 | 0.9993 |
| Alpelisib | 180622_MC_16 | 19135 | 0.0265 | 86 | 424 | 13 | 22 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 510 | 0.0260 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00189 | 0.9904 |
| Alpelisib | 180622_MC_14 | 19980 | 0.0261 | 51 | 471 | 3 | 12 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 522 | 0.0255 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00139 | 1.0122 |
| Alpelisib | 180622_MC_14 | 18935 | 0.0234 | 44 | 400 | 13 | 15 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_2 | 444 | 0.0229 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00116 | 0.9851 |
| Alpelisib | 180622_MC_14 | 18953 | 0.0252 | 47 | 431 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_3 | 478 | 0.0246 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00053 | 0.9856 |
| Alpelisib | 180622_MC_15 | 19746 | 0.0196 | 55 | 334 | 5 | 4 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_4 | 389 | 0.0193 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00475 | 1.0062 |
| Alpelisib | 180622_MC_15 | 19599 | 0.0257 | 75 | 431 | 10 | 21 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_5 | 506 | 0.0252 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00110 | 1.0024 |
| Alpelisib | 180622_MC_15 | 17832 | 0.0200 | 56 | 302 | 12 | 5 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_6 | 358 | 0.0197 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00439 | 0.9552 |
| Alpelisib | 180622_MC_16 | 18747 | 0.0249 | 81 | 388 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 469 | 0.0244 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00034 | 0.9801 |
| Alpelisib | 180622_MC_16 | 19514 | 0.0222 | 54 | 381 | 14 | 4 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 435 | 0.0218 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00226 | 1.0002 |
| Alpelisib | 180622_MC_16 | 19301 | 0.0212 | 73 | 337 | 14 | 10 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_9 | 410 | 0.0208 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00327 | 0.9947 |
| Alpelisib | 180622_MC_14 | 18229 | 0.0230 | 48 | 373 | 13 | 4 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_1 | 421 | 0.0226 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00149 | 0.9661 |
| Alpelisib | 180622_MC_14 | 18047 | 0.0249 | 61 | 390 | 13 | 13 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_2 | 451 | 0.0244 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00031 | 0.9612 |
| Alpelisib | 180622_MC_14 | 18371 | 0.0202 | 50 | 323 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_3 | 373 | 0.0199 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00417 | 0.9700 |
| Alpelisib | 180622_MC_15 | 19739 | 0.0253 | 61 | 439 | 3 | 18 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_4 | 500 | 0.0247 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00064 | 1.0060 |
| Alpelisib | 180622_MC_15 | 18915 | 0.0218 | 58 | 356 | 6 | 7 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_5 | 414 | 0.0214 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00265 | 0.9845 |