LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpelisib | 180615_MC_06 | 12313 | 0.0259 | 48 | 272 | 7 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 320 | 0.0253 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00193 | 0.9958 |
| Alpelisib | 180615_MC_06 | 13018 | 0.0255 | 38 | 295 | 8 | 11 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 333 | 0.0249 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00154 | 1.0211 |
| Alpelisib | 180615_MC_06 | 12114 | 0.0315 | 59 | 324 | 12 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_3 | 383 | 0.0306 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00725 | 0.9884 |
| Alpelisib | 180615_MC_07 | 11824 | 0.0169 | 44 | 156 | 3 | 13 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_4 | 200 | 0.0166 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00676 | 0.9775 |
| Alpelisib | 180615_MC_07 | 12386 | 0.0235 | 57 | 236 | 8 | 17 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_5 | 293 | 0.0231 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00029 | 0.9984 |
| Alpelisib | 180615_MC_07 | 11742 | 0.0162 | 12 | 178 | 13 | 15 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_6 | 190 | 0.0159 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00747 | 0.9744 |
| Alpelisib | 180615_MC_08 | 11920 | 0.0224 | 47 | 221 | 9 | 21 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_7 | 268 | 0.0220 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00141 | 0.9811 |
| Alpelisib | 180615_MC_08 | 12700 | 0.0264 | 74 | 263 | 11 | 6 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_8 | 337 | 0.0258 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00245 | 1.0098 |
| Alpelisib | 180615_MC_08 | 12239 | 0.0256 | 32 | 282 | 13 | 22 | Alpelisib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_9 | 314 | 0.0250 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00162 | 0.9930 |
| Alpelisib | 180615_MC_06 | 11595 | 0.0268 | 37 | 275 | 3 | 12 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_1 | 312 | 0.0262 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00280 | 0.9687 |
| Alpelisib | 180615_MC_06 | 12301 | 0.0193 | 16 | 222 | 13 | 15 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 238 | 0.0190 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00442 | 0.9953 |
| Alpelisib | 180615_MC_06 | 11270 | 0.0214 | 16 | 226 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 242 | 0.0210 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00238 | 0.9561 |
| Alpelisib | 180615_MC_07 | 11604 | 0.0182 | 38 | 174 | 5 | 4 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_4 | 212 | 0.0179 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00546 | 0.9691 |
| Alpelisib | 180615_MC_07 | 12379 | 0.0219 | 60 | 212 | 10 | 21 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 272 | 0.0215 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00190 | 0.9982 |
| Alpelisib | 180615_MC_07 | 12069 | 0.0183 | 36 | 185 | 12 | 5 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_6 | 221 | 0.0180 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00542 | 0.9867 |
| Alpelisib | 180615_MC_08 | 11963 | 0.0216 | 25 | 234 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_7 | 259 | 0.0212 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00221 | 0.9827 |
| Alpelisib | 180615_MC_08 | 12727 | 0.0210 | 56 | 213 | 14 | 4 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_8 | 269 | 0.0207 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00270 | 1.0108 |
| Alpelisib | 180615_MC_08 | 13012 | 0.0247 | 55 | 268 | 14 | 10 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_9 | 323 | 0.0242 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00082 | 1.0209 |
| Alpelisib | 180615_MC_06 | 10959 | 0.0247 | 18 | 253 | 13 | 4 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_1 | 271 | 0.0241 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00073 | 0.9437 |
| Alpelisib | 180615_MC_06 | 11201 | 0.0238 | 21 | 246 | 13 | 13 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_2 | 267 | 0.0233 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00012 | 0.9533 |
| Alpelisib | 180615_MC_06 | 12415 | 0.0248 | 22 | 286 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_3 | 308 | 0.0242 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00081 | 0.9995 |
| Alpelisib | 180615_MC_07 | 12324 | 0.0178 | 44 | 176 | 3 | 18 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_4 | 220 | 0.0175 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00586 | 0.9962 |
| Alpelisib | 180615_MC_07 | 11237 | 0.0164 | 44 | 141 | 6 | 7 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_5 | 185 | 0.0162 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00720 | 0.9548 |
| Alpelisib | 180615_MC_07 | 10996 | 0.0150 | 27 | 138 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_6 | 165 | 0.0148 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00861 | 0.9452 |
| Alpelisib | 180615_MC_08 | 11774 | 0.0241 | 50 | 235 | 5 | 18 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_7 | 285 | 0.0236 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00024 | 0.9756 |