LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vorinostat | 180619_MC_10 | 3664 | 0.0387 | 84 | 61 | 5 | 5 | Vorinostat | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_1 | 145 | 0.0381 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.01499 | 0.4674 |
Vorinostat | 180619_MC_10 | 3916 | 0.0291 | 68 | 48 | 7 | 10 | Vorinostat | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_2 | 116 | 0.0288 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00570 | 0.4889 |
Vorinostat | 180619_MC_10 | 4167 | 0.0300 | 71 | 56 | 8 | 8 | Vorinostat | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_3 | 127 | 0.0296 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00650 | 0.5093 |
Vorinostat | 180619_MC_11 | 4419 | 0.0296 | 69 | 64 | 6 | 20 | Vorinostat | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_4 | 133 | 0.0292 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00614 | 0.5288 |
Vorinostat | 180619_MC_11 | 4494 | 0.0286 | 59 | 71 | 12 | 17 | Vorinostat | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_5 | 130 | 0.0281 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00504 | 0.5345 |
Vorinostat | 180619_MC_11 | 4471 | 0.0250 | 52 | 61 | 14 | 21 | Vorinostat | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_6 | 113 | 0.0247 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00158 | 0.5328 |
Vorinostat | 180619_MC_12 | 5496 | 0.0416 | 151 | 84 | 3 | 9 | Vorinostat | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_7 | 235 | 0.0410 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.01793 | 0.6036 |
Vorinostat | 180619_MC_12 | 5046 | 0.0284 | 68 | 77 | 6 | 18 | Vorinostat | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_8 | 145 | 0.0279 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00486 | 0.5739 |
Vorinostat | 180619_MC_12 | 5288 | 0.0237 | 73 | 54 | 10 | 8 | Vorinostat | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_9 | 127 | 0.0235 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00038 | 0.5901 |
Vorinostat | 180619_MC_10 | 1107 | 0.0908 | 83 | 25 | 6 | 20 | Vorinostat | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_1 | 108 | 0.0889 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.06581 | 0.1291 |
Vorinostat | 180619_MC_10 | 1141 | 0.0902 | 78 | 32 | 7 | 8 | Vorinostat | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_2 | 110 | 0.0879 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.06486 | 0.1366 |
Vorinostat | 180619_MC_10 | 774 | 0.0999 | 57 | 26 | 11 | 12 | Vorinostat | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_3 | 83 | 0.0968 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.07378 | 0.0440 |
Vorinostat | 180619_MC_11 | 1353 | 0.1031 | 111 | 40 | 7 | 13 | Vorinostat | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_4 | 151 | 0.1004 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.07732 | 0.1798 |
Vorinostat | 180619_MC_11 | 1220 | 0.1378 | 144 | 44 | 9 | 11 | Vorinostat | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_5 | 188 | 0.1335 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.11045 | 0.1534 |
Vorinostat | 180619_MC_11 | 1382 | 0.0614 | 68 | 21 | 12 | 10 | Vorinostat | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_6 | 89 | 0.0605 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.03743 | 0.1853 |
Vorinostat | 180619_MC_12 | 1353 | 0.0968 | 103 | 38 | 6 | 6 | Vorinostat | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_4 | 141 | 0.0944 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.07130 | 0.1798 |
Vorinostat | 180619_MC_12 | 1490 | 0.1115 | 143 | 39 | 9 | 17 | Vorinostat | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_7 | 182 | 0.1089 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.08578 | 0.2050 |
Vorinostat | 180619_MC_12 | 1597 | 0.0809 | 109 | 29 | 10 | 17 | Vorinostat | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_8 | 138 | 0.0795 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.05646 | 0.2234 |
Vorinostat | 180619_MC_10 | 796 | 0.1208 | 73 | 32 | 10 | 16 | Vorinostat | 9.98 | treatment | 72 | 2 | MCF10A-GM_1 | 105 | 0.1165 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.09346 | 0.0504 |
Vorinostat | 180619_MC_10 | 702 | 0.1395 | 65 | 42 | 11 | 5 | Vorinostat | 9.98 | treatment | 72 | 2 | MCF10A-GM_2 | 107 | 0.1323 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.10919 | 0.0219 |
Vorinostat | 180619_MC_10 | 667 | 0.1344 | 62 | 36 | 13 | 5 | Vorinostat | 9.98 | treatment | 72 | 2 | MCF10A-GM_3 | 98 | 0.1281 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.10503 | 0.0105 |
Vorinostat | 180619_MC_11 | 897 | 0.1403 | 101 | 39 | 4 | 19 | Vorinostat | 9.98 | treatment | 72 | 2 | MCF10A-GM_4 | 140 | 0.1350 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.11193 | 0.0782 |
Vorinostat | 180619_MC_11 | 846 | 0.1688 | 114 | 48 | 5 | 17 | Vorinostat | 9.98 | treatment | 72 | 2 | MCF10A-GM_5 | 162 | 0.1607 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.13764 | 0.0645 |
Vorinostat | 180619_MC_11 | 821 | 0.1570 | 109 | 37 | 13 | 13 | Vorinostat | 9.98 | treatment | 72 | 2 | MCF10A-GM_6 | 146 | 0.1510 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.12791 | 0.0575 |
Vorinostat | 180619_MC_12 | 586 | 0.1965 | 106 | 30 | 10 | 4 | Vorinostat | 9.98 | treatment | 72 | 2 | MCF10A-GM_7 | 136 | 0.1884 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.16529 | -0.0177 |