LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
Data Columns
Download: Excel (XLSX), Comma-separated (CSV)
- 24 Data Columns
| Name | Description | Display Name | Data Type | Unit | Precision | Readout Type | Replicate | Comments |
|---|---|---|---|---|---|---|---|---|
| smallMolecule | Small molecule perturbagen | Small Molecule | small_molecule | |||||
| barcode | Unique identifier for a given 384/96 well plate | barcode | Text | |||||
| well | Name of the well on the 384/96 well plate | well | Text | |||||
| cellCount | Number of cells quantified as live in a given well | cell_count | Numeric | 0 | ||||
| fracDead | Fraction of cells quantified as dead in a given well | frac_dead | Numeric | 4 | ||||
| corpseCount | Number of cells quantified as dead (Hoesht negative, LDR positive cells) in a given well | corpse_count | Numeric | 0 | ||||
| cellCountDead | Number of cells quantified as dead (Hoescnt positive, LDR positive) in a given well | cell_count_dead | Numeric | 0 | ||||
| row | Name of row for a given well on the 384/96 well plate | row | Numeric | 0 | ||||
| column | Column number for a given well on the 384/96 well plate | column | Numeric | 0 | ||||
| agent | Name of the drug or treatment in a given well | agent | Text | |||||
| concentration | Concentration of the drug in micromolar in a given well | concentration | Text | |||||
| role | Role of the drug i.e treatment, positive control or negative control | role | Text | |||||
| timepoint | Duration of time (in hours) fo which the cell was treated prior to measurement | timepoint | Numeric | 0 | ||||
| replicate | If a condition is repeated 2 or more times on a single plate, a unique replicate number is assigned (1, 2, or 3) to each replicate condition | replicate | Numeric | 0 | ||||
| cellLine | Name of the cell line in a given well | cell_line | Text | |||||
| deadCount | cell_count__dead + corpse_count | dead_count | Numeric | 0 | ||||
| fractionDead | Fraction of cells quantified as dead in a given well | fraction_dead | Numeric | 4 | ||||
| cellCountTime0 | Mean number of cells quantified as alive in time=0 control plate | cell_count__time0 | Numeric | 1 | ||||
| deadCountTime0 | Mean number of cells quantified as dead in time=0 control plate | dead_count__time0 | Numeric | 1 | ||||
| cellCountCtrl | Mean number of cells quantified as alive in DMSO control (t=72 hrs) | cell_count__ctrl | Numeric | 0 | ||||
| deadCountCtrl | Mean number of cells quantified as dead in DMSO control wells (t=72 hrs) | dead_count__ctrl | Numeric | 1 | ||||
| fractionDeadCtrl | Mean fraction of cells quatified as dead in DMSO control wells | fraction_dead__ctrl | Numeric | 4 | ||||
| increaseFractionDead | Increase in the fraction of dead cells relative to time=0 control | increase_fraction_dead | Numeric | 5 | ||||
| gRvalue | Growth corrected dose response for a given well/condition | GRvalue | Numeric | 4 |
- 24 Data Columns