LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Taxol | 180619_MC_10 | 182 | 1.1074 | 302 | 234 | 3 | 19 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_1 | 536 | 0.7465 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.72344 | -0.2396 |
Taxol | 180619_MC_10 | 211 | 1.0693 | 193 | 239 | 11 | 7 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_2 | 432 | 0.6719 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.64878 | -0.2146 |
Taxol | 180619_MC_10 | 359 | 0.7662 | 150 | 240 | 12 | 16 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_3 | 390 | 0.5207 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.49762 | -0.1177 |
Taxol | 180619_MC_11 | 262 | 0.8493 | 196 | 193 | 4 | 16 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_4 | 389 | 0.5975 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.57447 | -0.1765 |
Taxol | 180619_MC_11 | 232 | 1.1323 | 282 | 300 | 9 | 10 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_5 | 582 | 0.7150 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.69191 | -0.1981 |
Taxol | 180619_MC_11 | 277 | 0.8565 | 169 | 213 | 10 | 14 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_6 | 382 | 0.5797 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.55659 | -0.1664 |
Taxol | 180619_MC_12 | 252 | 1.0820 | 309 | 298 | 4 | 20 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_7 | 607 | 0.7066 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.68356 | -0.1835 |
Taxol | 180619_MC_12 | 218 | 1.1855 | 348 | 323 | 7 | 8 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_8 | 671 | 0.7548 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.73171 | -0.2090 |
Taxol | 180619_MC_12 | 264 | 1.0333 | 337 | 284 | 11 | 18 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_9 | 621 | 0.7017 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.67862 | -0.1751 |
Taxol | 180619_MC_10 | 219 | 1.1072 | 294 | 274 | 4 | 14 | Paclitaxel | 0.099799981 | treatment | 72 | 2 | MCF10A-GM_1 | 568 | 0.7217 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.69865 | -0.2082 |
Taxol | 180619_MC_10 | 223 | 1.0587 | 339 | 256 | 5 | 14 | Paclitaxel | 0.099799981 | treatment | 72 | 2 | MCF10A-GM_2 | 595 | 0.7274 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.70431 | -0.2050 |
Taxol | 180619_MC_10 | 192 | 1.0669 | 152 | 215 | 6 | 7 | Paclitaxel | 0.099799981 | treatment | 72 | 2 | MCF10A-GM_3 | 367 | 0.6565 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.63346 | -0.2307 |
Taxol | 180619_MC_11 | 222 | 1.0303 | 240 | 236 | 10 | 22 | Paclitaxel | 0.099799981 | treatment | 72 | 2 | MCF10A-GM_4 | 476 | 0.6819 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.65887 | -0.2058 |
Taxol | 180619_MC_11 | 185 | 1.0670 | 248 | 214 | 11 | 17 | Paclitaxel | 0.099799981 | treatment | 72 | 2 | MCF10A-GM_5 | 462 | 0.7141 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.69099 | -0.2369 |
Taxol | 180619_MC_11 | 192 | 1.1138 | 265 | 244 | 14 | 20 | Paclitaxel | 0.099799981 | treatment | 72 | 2 | MCF10A-GM_3 | 509 | 0.7261 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.70303 | -0.2307 |
Taxol | 180619_MC_12 | 232 | 1.0296 | 377 | 250 | 3 | 20 | Paclitaxel | 0.099799981 | treatment | 72 | 2 | MCF10A-GM_6 | 627 | 0.7299 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.70684 | -0.1981 |
Taxol | 180619_MC_12 | 170 | 1.2075 | 447 | 298 | 9 | 13 | Paclitaxel | 0.099799981 | treatment | 72 | 2 | MCF10A-GM_7 | 745 | 0.8142 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.79113 | -0.2509 |
Taxol | 180619_MC_12 | 153 | 1.2797 | 344 | 292 | 14 | 5 | Paclitaxel | 0.099799981 | treatment | 72 | 2 | MCF10A-GM_8 | 636 | 0.8061 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.78301 | -0.2680 |
Taxol | 180619_MC_10 | 172 | 1.0344 | 177 | 184 | 4 | 18 | Paclitaxel | 0.312706472 | treatment | 72 | 2 | MCF10A-GM_1 | 361 | 0.6773 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.65422 | -0.2490 |
Taxol | 180619_MC_10 | 204 | 1.0740 | 269 | 239 | 7 | 19 | Paclitaxel | 0.312706472 | treatment | 72 | 2 | MCF10A-GM_2 | 508 | 0.7135 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.69041 | -0.2204 |
Taxol | 180619_MC_10 | 142 | 1.2687 | 260 | 250 | 8 | 3 | Paclitaxel | 0.312706472 | treatment | 72 | 2 | MCF10A-GM_3 | 510 | 0.7822 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.75913 | -0.2798 |
Taxol | 180619_MC_11 | 215 | 0.9824 | 183 | 208 | 4 | 12 | Paclitaxel | 0.312706472 | treatment | 72 | 2 | MCF10A-GM_4 | 391 | 0.6452 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.62214 | -0.2114 |
Taxol | 180619_MC_11 | 192 | 1.1699 | 279 | 272 | 11 | 15 | Paclitaxel | 0.312706472 | treatment | 72 | 2 | MCF10A-GM_5 | 551 | 0.7416 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.71851 | -0.2307 |
Taxol | 180619_MC_11 | 174 | 1.1342 | 288 | 236 | 13 | 9 | Paclitaxel | 0.312706472 | treatment | 72 | 2 | MCF10A-GM_6 | 524 | 0.7507 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.72764 | -0.2471 |
Taxol | 180619_MC_12 | 190 | 1.0164 | 298 | 198 | 7 | 21 | Paclitaxel | 0.312706472 | treatment | 72 | 2 | MCF10A-GM_7 | 496 | 0.7230 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.69996 | -0.2324 |