LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Taxol | 180619_MC_12 | 212 | 1.0811 | 244 | 249 | 10 | 22 | Paclitaxel | 0.312706472 | treatment | 72 | 2 | MCF10A-GM_8 | 493 | 0.6993 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.67622 | -0.2138 |
Taxol | 180619_MC_12 | 182 | 1.2080 | 366 | 296 | 14 | 15 | Paclitaxel | 0.312706472 | treatment | 72 | 2 | MCF10A-GM_9 | 662 | 0.7844 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.76129 | -0.2396 |
Palbociclib | 180619_MC_10 | 15595 | 0.0178 | 46 | 233 | 10 | 12 | Palbociclib | 0.001081167 | treatment | 72 | 2 | MCF10A-GM_1 | 279 | 0.0176 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00550 | 1.0150 |
Palbociclib | 180619_MC_10 | 13388 | 0.0204 | 64 | 211 | 11 | 9 | Palbociclib | 0.001081167 | treatment | 72 | 2 | MCF10A-GM_2 | 275 | 0.0201 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00295 | 0.9488 |
Palbociclib | 180619_MC_10 | 15589 | 0.0204 | 39 | 280 | 14 | 10 | Palbociclib | 0.001081167 | treatment | 72 | 2 | MCF10A-GM_3 | 319 | 0.0201 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00302 | 1.0149 |
Palbociclib | 180619_MC_11 | 14160 | 0.0246 | 60 | 290 | 6 | 19 | Palbociclib | 0.001081167 | treatment | 72 | 2 | MCF10A-GM_4 | 350 | 0.0241 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00105 | 0.9729 |
Palbociclib | 180619_MC_11 | 15080 | 0.0213 | 48 | 274 | 12 | 14 | Palbociclib | 0.001081167 | treatment | 72 | 2 | MCF10A-GM_5 | 322 | 0.0209 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00217 | 1.0003 |
Palbociclib | 180619_MC_11 | 14226 | 0.0231 | 85 | 245 | 13 | 6 | Palbociclib | 0.001081167 | treatment | 72 | 2 | MCF10A-GM_6 | 330 | 0.0227 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00040 | 0.9749 |
Palbociclib | 180619_MC_12 | 16041 | 0.0242 | 115 | 276 | 8 | 20 | Palbociclib | 0.001081167 | treatment | 72 | 2 | MCF10A-GM_7 | 391 | 0.0238 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00072 | 1.0275 |
Palbociclib | 180619_MC_12 | 16368 | 0.0214 | 75 | 277 | 12 | 6 | Palbociclib | 0.001081167 | treatment | 72 | 2 | MCF10A-GM_8 | 352 | 0.0211 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00202 | 1.0365 |
Palbociclib | 180619_MC_12 | 15490 | 0.0275 | 119 | 311 | 13 | 6 | Palbociclib | 0.001081167 | treatment | 72 | 2 | MCF10A-GM_9 | 430 | 0.0270 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00394 | 1.0120 |
Palbociclib | 180619_MC_10 | 13466 | 0.0195 | 53 | 211 | 12 | 17 | Palbociclib | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_1 | 264 | 0.0192 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00385 | 0.9513 |
Palbociclib | 180619_MC_10 | 15010 | 0.0207 | 43 | 269 | 13 | 8 | Palbociclib | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_2 | 312 | 0.0204 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00271 | 0.9982 |
Palbociclib | 180619_MC_10 | 13856 | 0.0207 | 59 | 229 | 13 | 10 | Palbociclib | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_3 | 288 | 0.0204 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00271 | 0.9635 |
Palbociclib | 180619_MC_11 | 15021 | 0.0212 | 64 | 256 | 6 | 3 | Palbociclib | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_4 | 320 | 0.0209 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00222 | 0.9985 |
Palbociclib | 180619_MC_11 | 14842 | 0.0231 | 59 | 285 | 8 | 15 | Palbociclib | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_5 | 344 | 0.0227 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00042 | 0.9933 |
Palbociclib | 180619_MC_11 | 14348 | 0.0219 | 69 | 247 | 13 | 7 | Palbociclib | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_6 | 316 | 0.0215 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00152 | 0.9786 |
Palbociclib | 180619_MC_12 | 14973 | 0.0224 | 75 | 262 | 4 | 15 | Palbociclib | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_7 | 337 | 0.0220 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00106 | 0.9971 |
Palbociclib | 180619_MC_12 | 15040 | 0.0349 | 186 | 345 | 7 | 5 | Palbociclib | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_8 | 531 | 0.0341 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.01103 | 0.9991 |
Palbociclib | 180619_MC_12 | 15446 | 0.0237 | 94 | 274 | 8 | 7 | Palbociclib | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_9 | 368 | 0.0233 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00020 | 1.0108 |
Palbociclib | 180619_MC_10 | 11967 | 0.0184 | 47 | 174 | 5 | 22 | Palbociclib | 0.00998 | treatment | 72 | 2 | MCF10A-GM_1 | 221 | 0.0181 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00494 | 0.9015 |
Palbociclib | 180619_MC_10 | 13256 | 0.0248 | 69 | 262 | 6 | 3 | Palbociclib | 0.00998 | treatment | 72 | 2 | MCF10A-GM_2 | 331 | 0.0244 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00129 | 0.9446 |
Palbociclib | 180619_MC_10 | 12731 | 0.0145 | 39 | 146 | 14 | 22 | Palbociclib | 0.00998 | treatment | 72 | 2 | MCF10A-GM_3 | 185 | 0.0143 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00875 | 0.9275 |
Palbociclib | 180619_MC_11 | 14254 | 0.0175 | 53 | 198 | 12 | 22 | Palbociclib | 0.00998 | treatment | 72 | 2 | MCF10A-GM_4 | 251 | 0.0173 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00577 | 0.9757 |
Palbociclib | 180619_MC_11 | 15356 | 0.0192 | 43 | 253 | 13 | 10 | Palbociclib | 0.00998 | treatment | 72 | 2 | MCF10A-GM_5 | 296 | 0.0189 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00416 | 1.0082 |