LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180622_MC_15 | 18651 | 0.0273 | 94 | 418 | 13 | 3 | Neratinib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_6 | 512 | 0.0267 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00265 | 0.9775 |
| Neratinib | 180622_MC_16 | 19801 | 0.0279 | 77 | 478 | 4 | 9 | Neratinib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_7 | 555 | 0.0273 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00320 | 1.0076 |
| Neratinib | 180622_MC_16 | 19132 | 0.0228 | 102 | 337 | 8 | 15 | Neratinib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_8 | 439 | 0.0224 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00164 | 0.9903 |
| Neratinib | 180622_MC_16 | 20035 | 0.0240 | 68 | 414 | 8 | 18 | Neratinib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_9 | 482 | 0.0235 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00057 | 1.0136 |
| Neratinib | 180622_MC_14 | 8986 | 0.0180 | 47 | 116 | 11 | 14 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_1 | 163 | 0.0178 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00625 | 0.6446 |
| Neratinib | 180622_MC_14 | 11115 | 0.0147 | 42 | 122 | 14 | 15 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_2 | 164 | 0.0145 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00953 | 0.7353 |
| Neratinib | 180622_MC_14 | 9186 | 0.0197 | 63 | 119 | 14 | 18 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_3 | 182 | 0.0194 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00464 | 0.6538 |
| Neratinib | 180622_MC_15 | 17274 | 0.0202 | 35 | 315 | 6 | 5 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_4 | 350 | 0.0199 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00421 | 0.9396 |
| Neratinib | 180622_MC_15 | 16600 | 0.0216 | 77 | 284 | 8 | 6 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_5 | 361 | 0.0213 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00278 | 0.9202 |
| Neratinib | 180622_MC_15 | 17214 | 0.0233 | 102 | 302 | 9 | 5 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_6 | 404 | 0.0229 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00114 | 0.9379 |
| Neratinib | 180622_MC_16 | 19290 | 0.0278 | 84 | 454 | 8 | 5 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_7 | 538 | 0.0271 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00307 | 0.9944 |
| Neratinib | 180622_MC_16 | 19385 | 0.0219 | 83 | 343 | 11 | 15 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_8 | 426 | 0.0215 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00256 | 0.9969 |
| Neratinib | 180622_MC_16 | 18939 | 0.0246 | 75 | 393 | 12 | 7 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_9 | 468 | 0.0241 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00005 | 0.9852 |
| Neratinib | 180622_MC_14 | 4032 | 0.0337 | 65 | 73 | 3 | 5 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_1 | 138 | 0.0331 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00903 | 0.3434 |
| Neratinib | 180622_MC_14 | 3977 | 0.0236 | 47 | 48 | 10 | 8 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_2 | 95 | 0.0233 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00074 | 0.3388 |
| Neratinib | 180622_MC_14 | 3984 | 0.0231 | 40 | 53 | 11 | 19 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_3 | 93 | 0.0228 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00126 | 0.3394 |
| Neratinib | 180622_MC_15 | 6499 | 0.0246 | 76 | 86 | 3 | 22 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_4 | 162 | 0.0243 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00025 | 0.5155 |
| Neratinib | 180622_MC_15 | 7144 | 0.0233 | 94 | 75 | 9 | 16 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_5 | 169 | 0.0231 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00096 | 0.5521 |
| Neratinib | 180622_MC_15 | 6469 | 0.0213 | 58 | 81 | 14 | 9 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_6 | 139 | 0.0210 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00303 | 0.5137 |
| Neratinib | 180622_MC_16 | 10887 | 0.0255 | 97 | 183 | 4 | 6 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_7 | 280 | 0.0251 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00101 | 0.7263 |
| Neratinib | 180622_MC_16 | 10204 | 0.0247 | 100 | 154 | 5 | 17 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_8 | 254 | 0.0243 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00022 | 0.6983 |
| Neratinib | 180622_MC_16 | 9701 | 0.0236 | 122 | 110 | 9 | 16 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_9 | 232 | 0.0234 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00071 | 0.6767 |
| Neratinib | 180622_MC_14 | 1475 | 0.1149 | 92 | 88 | 10 | 3 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_1 | 180 | 0.1088 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.08469 | 0.0422 |
| Neratinib | 180622_MC_14 | 1904 | 0.0808 | 63 | 96 | 10 | 21 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_2 | 159 | 0.0771 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05300 | 0.1116 |
| Neratinib | 180622_MC_14 | 1760 | 0.0547 | 33 | 65 | 11 | 20 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_3 | 98 | 0.0527 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02868 | 0.0898 |