LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180622_MC_15 | 3157 | 0.0452 | 95 | 52 | 3 | 12 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_4 | 147 | 0.0445 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02042 | 0.2630 |
| Neratinib | 180622_MC_15 | 2746 | 0.0360 | 59 | 42 | 9 | 8 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_5 | 101 | 0.0355 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.01141 | 0.2193 |
| Neratinib | 180622_MC_15 | 2868 | 0.0331 | 63 | 34 | 14 | 13 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_6 | 97 | 0.0327 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00865 | 0.2327 |
| Neratinib | 180622_MC_16 | 4895 | 0.0192 | 47 | 48 | 6 | 10 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_7 | 95 | 0.0190 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00503 | 0.4108 |
| Neratinib | 180622_MC_16 | 4541 | 0.0610 | 147 | 139 | 7 | 3 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_8 | 286 | 0.0593 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03518 | 0.3843 |
| Neratinib | 180622_MC_16 | 4796 | 0.0552 | 166 | 108 | 7 | 7 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_9 | 274 | 0.0540 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02998 | 0.4036 |
| Neratinib | 180622_MC_14 | 1602 | 0.1061 | 57 | 119 | 4 | 22 | Neratinib | 3.160329364 | treatment | 72 | 3 | MCF10A-GM_1 | 176 | 0.0990 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.07492 | 0.0642 |
| Neratinib | 180622_MC_14 | 1620 | 0.1536 | 60 | 198 | 5 | 19 | Neratinib | 3.160329364 | treatment | 72 | 3 | MCF10A-GM_2 | 258 | 0.1374 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.11331 | 0.0672 |
| Neratinib | 180622_MC_14 | 1643 | 0.1246 | 74 | 140 | 9 | 9 | Neratinib | 3.160329364 | treatment | 72 | 3 | MCF10A-GM_3 | 214 | 0.1152 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.09117 | 0.0710 |
| Neratinib | 180622_MC_15 | 1996 | 0.0866 | 49 | 128 | 5 | 12 | Neratinib | 3.160329364 | treatment | 72 | 3 | MCF10A-GM_4 | 177 | 0.0815 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.05739 | 0.1249 |
| Neratinib | 180622_MC_15 | 1946 | 0.1142 | 76 | 155 | 8 | 19 | Neratinib | 3.160329364 | treatment | 72 | 3 | MCF10A-GM_5 | 231 | 0.1061 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.08204 | 0.1178 |
| Neratinib | 180622_MC_15 | 1973 | 0.1167 | 101 | 141 | 9 | 20 | Neratinib | 3.160329364 | treatment | 72 | 3 | MCF10A-GM_6 | 242 | 0.1093 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.08519 | 0.1217 |
| Neratinib | 180622_MC_16 | 2496 | 0.0466 | 80 | 40 | 4 | 22 | Neratinib | 3.160329364 | treatment | 72 | 3 | MCF10A-GM_7 | 120 | 0.0459 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.02180 | 0.1902 |
| Neratinib | 180622_MC_16 | 2255 | 0.0628 | 84 | 63 | 8 | 14 | Neratinib | 3.160329364 | treatment | 72 | 3 | MCF10A-GM_8 | 147 | 0.0612 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03713 | 0.1601 |
| Neratinib | 180622_MC_16 | 1993 | 0.0633 | 77 | 54 | 13 | 14 | Neratinib | 3.160329364 | treatment | 72 | 3 | MCF10A-GM_9 | 131 | 0.0617 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.03761 | 0.1245 |
| Taxol | 180622_MC_14 | 19724 | 0.0297 | 63 | 525 | 7 | 15 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_1 | 588 | 0.0289 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00488 | 1.0056 |
| Taxol | 180622_MC_14 | 19849 | 0.0216 | 60 | 370 | 12 | 5 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_2 | 430 | 0.0212 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00286 | 1.0088 |
| Taxol | 180622_MC_14 | 19665 | 0.0263 | 56 | 462 | 13 | 7 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_3 | 518 | 0.0257 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00160 | 1.0041 |
| Taxol | 180622_MC_15 | 19723 | 0.0213 | 67 | 354 | 6 | 13 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_4 | 421 | 0.0209 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00317 | 1.0056 |
| Taxol | 180622_MC_15 | 20105 | 0.0244 | 72 | 420 | 8 | 13 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_5 | 492 | 0.0239 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00018 | 1.0154 |
| Taxol | 180622_MC_15 | 18625 | 0.0208 | 63 | 326 | 13 | 17 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_6 | 389 | 0.0205 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00361 | 0.9768 |
| Taxol | 180622_MC_16 | 20455 | 0.0283 | 110 | 471 | 9 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_7 | 581 | 0.0276 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00355 | 1.0242 |
| Taxol | 180622_MC_16 | 19774 | 0.0232 | 63 | 397 | 10 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_8 | 460 | 0.0227 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00133 | 1.0069 |
| Taxol | 180622_MC_16 | 19940 | 0.0243 | 70 | 417 | 13 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_9 | 487 | 0.0238 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00023 | 1.0112 |
| Taxol | 180622_MC_14 | 20043 | 0.0284 | 70 | 501 | 3 | 16 | Paclitaxel | 0.000998 | treatment | 72 | 3 | MCF10A-GM_1 | 571 | 0.0277 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00363 | 1.0138 |