LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
Download: Excel (XLSX), Comma-separated (CSV)
Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Taxol | 180622_MC_14 | 18618 | 0.0270 | 71 | 434 | 12 | 7 | Paclitaxel | 0.000998 | treatment | 72 | 3 | MCF10A-GM_2 | 505 | 0.0264 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00234 | 0.9766 |
Taxol | 180622_MC_14 | 17285 | 0.0229 | 66 | 331 | 14 | 5 | Paclitaxel | 0.000998 | treatment | 72 | 3 | MCF10A-GM_3 | 397 | 0.0225 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00162 | 0.9399 |
Taxol | 180622_MC_15 | 17725 | 0.0278 | 105 | 391 | 10 | 5 | Paclitaxel | 0.000998 | treatment | 72 | 3 | MCF10A-GM_4 | 496 | 0.0272 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00315 | 0.9523 |
Taxol | 180622_MC_15 | 17887 | 0.0249 | 79 | 369 | 12 | 4 | Paclitaxel | 0.000998 | treatment | 72 | 3 | MCF10A-GM_5 | 448 | 0.0244 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00037 | 0.9568 |
Taxol | 180622_MC_15 | 18120 | 0.0249 | 61 | 391 | 13 | 12 | Paclitaxel | 0.000998 | treatment | 72 | 3 | MCF10A-GM_6 | 452 | 0.0243 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00027 | 0.9632 |
Taxol | 180622_MC_16 | 19053 | 0.0257 | 81 | 411 | 10 | 15 | Paclitaxel | 0.000998 | treatment | 72 | 3 | MCF10A-GM_7 | 492 | 0.0252 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00110 | 0.9882 |
Taxol | 180622_MC_16 | 18994 | 0.0263 | 60 | 441 | 10 | 18 | Paclitaxel | 0.000998 | treatment | 72 | 3 | MCF10A-GM_8 | 501 | 0.0257 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00163 | 0.9866 |
Taxol | 180622_MC_16 | 18524 | 0.0207 | 61 | 324 | 12 | 12 | Paclitaxel | 0.000998 | treatment | 72 | 3 | MCF10A-GM_9 | 385 | 0.0204 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00371 | 0.9741 |
Taxol | 180622_MC_14 | 6744 | 0.1753 | 392 | 859 | 5 | 21 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_1 | 1251 | 0.1565 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.13241 | 0.5297 |
Taxol | 180622_MC_14 | 6438 | 0.1745 | 380 | 810 | 7 | 16 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_2 | 1190 | 0.1560 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.13194 | 0.5119 |
Taxol | 180622_MC_14 | 7008 | 0.1659 | 398 | 831 | 7 | 22 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_3 | 1229 | 0.1492 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.12514 | 0.5446 |
Taxol | 180622_MC_15 | 6837 | 0.1876 | 403 | 955 | 9 | 9 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_4 | 1358 | 0.1657 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.14164 | 0.5350 |
Taxol | 180622_MC_15 | 6607 | 0.1572 | 335 | 756 | 12 | 12 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_5 | 1091 | 0.1417 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.11766 | 0.5218 |
Taxol | 180622_MC_15 | 7714 | 0.1012 | 184 | 615 | 14 | 6 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_6 | 799 | 0.0939 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.06979 | 0.5825 |
Taxol | 180622_MC_16 | 7413 | 0.1415 | 406 | 700 | 5 | 15 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_7 | 1106 | 0.1298 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.10576 | 0.5666 |
Taxol | 180622_MC_16 | 9200 | 0.0913 | 246 | 616 | 8 | 8 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_8 | 862 | 0.0857 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.06160 | 0.6544 |
Taxol | 180622_MC_16 | 8302 | 0.1074 | 312 | 613 | 13 | 11 | Paclitaxel | 0.002994 | treatment | 72 | 3 | MCF10A-GM_9 | 925 | 0.1002 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.07618 | 0.6121 |
Taxol | 180622_MC_14 | 1324 | 0.6923 | 470 | 772 | 3 | 9 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_1 | 1242 | 0.4840 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.45995 | 0.0142 |
Taxol | 180622_MC_14 | 1275 | 0.7791 | 527 | 877 | 4 | 16 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_2 | 1404 | 0.5241 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.50001 | 0.0046 |
Taxol | 180622_MC_14 | 1450 | 0.7354 | 447 | 948 | 4 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_3 | 1395 | 0.4903 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.46627 | 0.0378 |
Taxol | 180622_MC_15 | 1507 | 0.6928 | 508 | 888 | 5 | 16 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_4 | 1396 | 0.4809 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.45681 | 0.0479 |
Taxol | 180622_MC_15 | 1490 | 0.6954 | 519 | 878 | 11 | 11 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_5 | 1397 | 0.4839 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.45983 | 0.0449 |
Taxol | 180622_MC_15 | 1553 | 0.7428 | 613 | 996 | 13 | 5 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_6 | 1609 | 0.5089 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.48479 | 0.0559 |
Taxol | 180622_MC_16 | 1943 | 0.6877 | 740 | 1105 | 3 | 14 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 1845 | 0.4871 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.46300 | 0.1173 |
Taxol | 180622_MC_16 | 1866 | 0.5198 | 333 | 810 | 12 | 20 | Paclitaxel | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 1143 | 0.3799 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.35579 | 0.1060 |