LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Alpelisib | 180622_MC_15 | 13810 | 0.0192 | 74 | 192 | 4 | 9 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_4 | 266 | 0.0189 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00517 | 0.8331 |
| Alpelisib | 180622_MC_15 | 14274 | 0.0219 | 87 | 227 | 5 | 13 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_5 | 314 | 0.0215 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00254 | 0.8484 |
| Alpelisib | 180622_MC_15 | 14245 | 0.0156 | 81 | 142 | 11 | 6 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_6 | 223 | 0.0154 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00865 | 0.8475 |
| Alpelisib | 180622_MC_16 | 13693 | 0.0196 | 105 | 166 | 4 | 12 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_7 | 271 | 0.0194 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00466 | 0.8291 |
| Alpelisib | 180622_MC_16 | 13855 | 0.0235 | 118 | 210 | 5 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_8 | 328 | 0.0231 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00094 | 0.8346 |
| Alpelisib | 180622_MC_16 | 14546 | 0.0269 | 114 | 280 | 7 | 18 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_9 | 394 | 0.0264 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00230 | 0.8572 |
| Alpelisib | 180622_MC_14 | 10933 | 0.0249 | 63 | 211 | 6 | 13 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_1 | 274 | 0.0244 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00038 | 0.7281 |
| Alpelisib | 180622_MC_14 | 10959 | 0.0243 | 71 | 197 | 8 | 7 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_2 | 268 | 0.0239 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00020 | 0.7291 |
| Alpelisib | 180622_MC_14 | 10518 | 0.0225 | 78 | 160 | 10 | 5 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_3 | 238 | 0.0221 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00194 | 0.7113 |
| Alpelisib | 180622_MC_15 | 11957 | 0.0230 | 129 | 149 | 8 | 4 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_4 | 278 | 0.0227 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00135 | 0.7676 |
| Alpelisib | 180622_MC_15 | 11567 | 0.0160 | 84 | 102 | 10 | 13 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_5 | 186 | 0.0158 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00824 | 0.7529 |
| Alpelisib | 180622_MC_15 | 11217 | 0.0155 | 76 | 99 | 11 | 21 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_6 | 175 | 0.0154 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00871 | 0.7393 |
| Alpelisib | 180622_MC_16 | 11351 | 0.0224 | 79 | 177 | 5 | 19 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_7 | 256 | 0.0221 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00201 | 0.7445 |
| Alpelisib | 180622_MC_16 | 11210 | 0.0175 | 77 | 121 | 10 | 10 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_8 | 198 | 0.0174 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00671 | 0.7390 |
| Alpelisib | 180622_MC_16 | 12442 | 0.0171 | 96 | 119 | 14 | 21 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_9 | 215 | 0.0170 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00708 | 0.7854 |
| Alpelisib | 180622_MC_14 | 7014 | 0.0259 | 78 | 106 | 8 | 17 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_1 | 184 | 0.0256 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00149 | 0.5449 |
| Alpelisib | 180622_MC_14 | 6708 | 0.0261 | 71 | 106 | 9 | 4 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_2 | 177 | 0.0257 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00164 | 0.5276 |
| Alpelisib | 180622_MC_14 | 6816 | 0.0257 | 62 | 115 | 12 | 19 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_3 | 177 | 0.0253 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00124 | 0.5338 |
| Alpelisib | 180622_MC_15 | 8266 | 0.0289 | 133 | 110 | 3 | 11 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_4 | 243 | 0.0286 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00449 | 0.6103 |
| Alpelisib | 180622_MC_15 | 7210 | 0.0273 | 70 | 129 | 5 | 22 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_5 | 199 | 0.0269 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00279 | 0.5557 |
| Alpelisib | 180622_MC_15 | 8262 | 0.0204 | 72 | 98 | 6 | 16 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_6 | 170 | 0.0202 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00391 | 0.6101 |
| Alpelisib | 180622_MC_16 | 8684 | 0.0253 | 106 | 116 | 9 | 22 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_7 | 222 | 0.0249 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | 0.00086 | 0.6305 |
| Alpelisib | 180622_MC_16 | 7708 | 0.0230 | 66 | 113 | 10 | 14 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_8 | 179 | 0.0227 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00137 | 0.5822 |
| Alpelisib | 180622_MC_16 | 8548 | 0.0204 | 85 | 91 | 14 | 14 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_9 | 176 | 0.0202 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00389 | 0.6240 |
| Dasatinib | 180622_MC_14 | 15827 | 0.0221 | 80 | 272 | 3 | 3 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 352 | 0.0218 | 1252.0 | 97.6 | 19505 | 481.8 | 0.0241 | -0.00231 | 0.8972 |