LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dasatinib | 180619_MC_12 | 1193 | 0.1832 | 139 | 105 | 9 | 4 | Dasatinib | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_8 | 244 | 0.1698 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.14672 | 0.1477 |
Dasatinib | 180619_MC_12 | 1897 | 0.1404 | 104 | 177 | 12 | 11 | Dasatinib | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_9 | 281 | 0.1290 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.10594 | 0.2704 |
Dasatinib | 180619_MC_10 | 706 | 0.3611 | 86 | 200 | 7 | 20 | Dasatinib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_1 | 286 | 0.2883 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.26523 | 0.0232 |
Dasatinib | 180619_MC_10 | 488 | 0.3676 | 56 | 144 | 12 | 3 | Dasatinib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_2 | 200 | 0.2907 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.26762 | -0.0563 |
Dasatinib | 180619_MC_10 | 839 | 0.2393 | 51 | 162 | 13 | 9 | Dasatinib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_3 | 213 | 0.2025 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.17940 | 0.0626 |
Dasatinib | 180619_MC_11 | 762 | 0.2769 | 47 | 177 | 12 | 8 | Dasatinib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_4 | 224 | 0.2272 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.20411 | 0.0404 |
Dasatinib | 180619_MC_11 | 967 | 0.2287 | 65 | 171 | 13 | 20 | Dasatinib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_5 | 236 | 0.1962 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.17310 | 0.0961 |
Dasatinib | 180619_MC_11 | 793 | 0.2867 | 65 | 181 | 13 | 22 | Dasatinib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_6 | 246 | 0.2368 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.21369 | 0.0495 |
Dasatinib | 180619_MC_12 | 906 | 0.3118 | 162 | 171 | 3 | 13 | Dasatinib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_7 | 333 | 0.2688 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.24569 | 0.0806 |
Dasatinib | 180619_MC_12 | 944 | 0.2570 | 95 | 172 | 4 | 11 | Dasatinib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_8 | 267 | 0.2205 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.19740 | 0.0904 |
Dasatinib | 180619_MC_12 | 884 | 0.2809 | 127 | 157 | 11 | 11 | Dasatinib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_9 | 284 | 0.2432 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.22008 | 0.0748 |
Dasatinib | 180619_MC_10 | 298 | 0.9678 | 106 | 285 | 4 | 13 | Dasatinib | 9.98 | treatment | 72 | 2 | MCF10A-GM_1 | 391 | 0.5675 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.54441 | -0.1529 |
Dasatinib | 180619_MC_10 | 274 | 0.9823 | 121 | 267 | 7 | 11 | Dasatinib | 9.98 | treatment | 72 | 2 | MCF10A-GM_2 | 388 | 0.5861 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.56303 | -0.1684 |
Dasatinib | 180619_MC_10 | 287 | 0.9156 | 116 | 253 | 8 | 19 | Dasatinib | 9.98 | treatment | 72 | 2 | MCF10A-GM_3 | 369 | 0.5625 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.53943 | -0.1599 |
Dasatinib | 180619_MC_11 | 328 | 0.8231 | 96 | 253 | 6 | 4 | Dasatinib | 9.98 | treatment | 72 | 2 | MCF10A-GM_4 | 349 | 0.5155 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.49244 | -0.1349 |
Dasatinib | 180619_MC_11 | 283 | 0.9894 | 190 | 278 | 7 | 19 | Dasatinib | 9.98 | treatment | 72 | 2 | MCF10A-GM_5 | 468 | 0.6232 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.60009 | -0.1624 |
Dasatinib | 180619_MC_11 | 273 | 0.9044 | 93 | 238 | 12 | 19 | Dasatinib | 9.98 | treatment | 72 | 2 | MCF10A-GM_6 | 331 | 0.5480 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.52494 | -0.1690 |
Dasatinib | 180619_MC_12 | 231 | 0.9471 | 185 | 209 | 5 | 8 | Dasatinib | 9.98 | treatment | 72 | 2 | MCF10A-GM_7 | 394 | 0.6304 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.60733 | -0.1989 |
Dasatinib | 180619_MC_12 | 261 | 0.9365 | 196 | 232 | 7 | 16 | Dasatinib | 9.98 | treatment | 72 | 2 | MCF10A-GM_8 | 428 | 0.6212 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.59812 | -0.1772 |
Dasatinib | 180619_MC_12 | 284 | 0.8345 | 127 | 216 | 11 | 16 | Dasatinib | 9.98 | treatment | 72 | 2 | MCF10A-GM_9 | 343 | 0.5470 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.52398 | -0.1618 |
Etoposide | 180619_MC_10 | 15497 | 0.0178 | 19 | 257 | 4 | 7 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_1 | 276 | 0.0175 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00558 | 1.0122 |
Etoposide | 180619_MC_10 | 14749 | 0.0208 | 56 | 252 | 5 | 10 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_2 | 308 | 0.0205 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00262 | 0.9906 |
Etoposide | 180619_MC_10 | 13248 | 0.0216 | 46 | 241 | 12 | 10 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_3 | 287 | 0.0212 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00187 | 0.9443 |
Etoposide | 180619_MC_11 | 14372 | 0.0221 | 78 | 241 | 10 | 3 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_4 | 319 | 0.0217 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00136 | 0.9793 |
Etoposide | 180619_MC_11 | 15289 | 0.0225 | 54 | 291 | 10 | 20 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_5 | 345 | 0.0221 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00101 | 1.0063 |