LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Etoposide | 180619_MC_11 | 14663 | 0.0137 | 42 | 160 | 12 | 18 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_6 | 202 | 0.0136 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00949 | 0.9880 |
Etoposide | 180619_MC_12 | 13759 | 0.0295 | 149 | 261 | 11 | 4 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_7 | 410 | 0.0289 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00586 | 0.9605 |
Etoposide | 180619_MC_12 | 13877 | 0.0327 | 172 | 287 | 11 | 7 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_8 | 459 | 0.0320 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00894 | 0.9642 |
Etoposide | 180619_MC_12 | 14937 | 0.0222 | 95 | 239 | 14 | 8 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_9 | 334 | 0.0219 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00120 | 0.9961 |
Etoposide | 180619_MC_10 | 14567 | 0.0236 | 79 | 267 | 9 | 5 | Etoposide | 0.00998 | treatment | 72 | 2 | MCF10A-GM_1 | 346 | 0.0232 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00013 | 0.9852 |
Etoposide | 180619_MC_10 | 13777 | 0.0216 | 90 | 210 | 9 | 17 | Etoposide | 0.00998 | treatment | 72 | 2 | MCF10A-GM_2 | 300 | 0.0213 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00176 | 0.9611 |
Etoposide | 180619_MC_10 | 13577 | 0.0166 | 40 | 186 | 12 | 20 | Etoposide | 0.00998 | treatment | 72 | 2 | MCF10A-GM_3 | 226 | 0.0164 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00670 | 0.9548 |
Etoposide | 180619_MC_11 | 14114 | 0.0185 | 63 | 199 | 4 | 3 | Etoposide | 0.00998 | treatment | 72 | 2 | MCF10A-GM_4 | 262 | 0.0182 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00485 | 0.9715 |
Etoposide | 180619_MC_11 | 14737 | 0.0207 | 44 | 262 | 6 | 14 | Etoposide | 0.00998 | treatment | 72 | 2 | MCF10A-GM_5 | 306 | 0.0203 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00273 | 0.9902 |
Etoposide | 180619_MC_11 | 14888 | 0.0220 | 66 | 263 | 8 | 14 | Etoposide | 0.00998 | treatment | 72 | 2 | MCF10A-GM_6 | 329 | 0.0216 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00145 | 0.9947 |
Etoposide | 180619_MC_12 | 13699 | 0.0302 | 164 | 254 | 7 | 6 | Etoposide | 0.00998 | treatment | 72 | 2 | MCF10A-GM_7 | 418 | 0.0296 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00654 | 0.9586 |
Etoposide | 180619_MC_12 | 14612 | 0.0243 | 105 | 253 | 8 | 6 | Etoposide | 0.00998 | treatment | 72 | 2 | MCF10A-GM_8 | 358 | 0.0239 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00084 | 0.9865 |
Etoposide | 180619_MC_12 | 15260 | 0.0220 | 76 | 262 | 12 | 17 | Etoposide | 0.00998 | treatment | 72 | 2 | MCF10A-GM_9 | 338 | 0.0217 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00140 | 1.0055 |
Etoposide | 180619_MC_10 | 12190 | 0.0218 | 70 | 197 | 9 | 12 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_1 | 267 | 0.0214 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00164 | 0.9092 |
Etoposide | 180619_MC_10 | 11770 | 0.0190 | 63 | 162 | 11 | 21 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_2 | 225 | 0.0188 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00432 | 0.8946 |
Etoposide | 180619_MC_10 | 10930 | 0.0156 | 38 | 133 | 14 | 9 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_3 | 171 | 0.0154 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00767 | 0.8641 |
Etoposide | 180619_MC_11 | 11229 | 0.0229 | 54 | 204 | 5 | 9 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_4 | 258 | 0.0225 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00061 | 0.8752 |
Etoposide | 180619_MC_11 | 11814 | 0.0205 | 63 | 181 | 12 | 7 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_5 | 244 | 0.0202 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00284 | 0.8962 |
Etoposide | 180619_MC_11 | 12203 | 0.0186 | 67 | 161 | 12 | 11 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_6 | 228 | 0.0183 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00473 | 0.9097 |
Etoposide | 180619_MC_12 | 12993 | 0.0279 | 130 | 236 | 3 | 12 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_7 | 366 | 0.0274 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00432 | 0.9361 |
Etoposide | 180619_MC_12 | 13441 | 0.0221 | 94 | 205 | 4 | 10 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_8 | 299 | 0.0218 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00131 | 0.9505 |
Etoposide | 180619_MC_12 | 14317 | 0.0255 | 143 | 226 | 9 | 14 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_9 | 369 | 0.0251 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | 0.00205 | 0.9776 |
Etoposide | 180619_MC_10 | 7535 | 0.0207 | 83 | 75 | 7 | 4 | Etoposide | 0.099799999 | treatment | 72 | 2 | MCF10A-GM_1 | 158 | 0.0205 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00254 | 0.7183 |
Etoposide | 180619_MC_10 | 7822 | 0.0224 | 93 | 84 | 9 | 13 | Etoposide | 0.099799999 | treatment | 72 | 2 | MCF10A-GM_2 | 177 | 0.0221 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00095 | 0.7325 |
Etoposide | 180619_MC_10 | 6868 | 0.0185 | 55 | 73 | 14 | 17 | Etoposide | 0.099799999 | treatment | 72 | 2 | MCF10A-GM_3 | 128 | 0.0183 | 635.9 | 71.1 | 15071 | 356.7 | 0.0231 | -0.00478 | 0.6838 |