LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trametinib | 180615_MC_08 | 1098 | 0.0672 | 48 | 29 | 10 | 5 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_8 | 77 | 0.0655 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04213 | 0.1531 |
Trametinib | 180615_MC_08 | 1228 | 0.0940 | 81 | 42 | 11 | 10 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_9 | 123 | 0.0910 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.06765 | 0.1827 |
Trametinib | 180615_MC_06 | 1010 | 0.0632 | 34 | 32 | 4 | 17 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_1 | 66 | 0.0613 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03794 | 0.1314 |
Trametinib | 180615_MC_06 | 873 | 0.0716 | 21 | 43 | 8 | 13 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_2 | 64 | 0.0683 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04490 | 0.0946 |
Trametinib | 180615_MC_06 | 1086 | 0.0739 | 37 | 46 | 11 | 10 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_3 | 83 | 0.0710 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04760 | 0.1502 |
Trametinib | 180615_MC_07 | 806 | 0.1095 | 43 | 50 | 4 | 22 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_4 | 93 | 0.1034 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08005 | 0.0749 |
Trametinib | 180615_MC_07 | 1095 | 0.1367 | 90 | 72 | 8 | 12 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_5 | 162 | 0.1289 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.10548 | 0.1523 |
Trametinib | 180615_MC_07 | 991 | 0.0742 | 33 | 43 | 14 | 7 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_6 | 76 | 0.0712 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04783 | 0.1265 |
Trametinib | 180615_MC_08 | 847 | 0.1444 | 81 | 53 | 6 | 13 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_7 | 134 | 0.1366 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.11320 | 0.0871 |
Trametinib | 180615_MC_08 | 921 | 0.1228 | 64 | 57 | 8 | 9 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_8 | 121 | 0.1161 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.09272 | 0.1080 |
Trametinib | 180615_MC_08 | 834 | 0.1010 | 57 | 33 | 10 | 21 | Trametinib | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_9 | 90 | 0.0974 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.07400 | 0.0833 |
Trametinib | 180615_MC_06 | 920 | 0.1249 | 81 | 44 | 3 | 20 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_1 | 125 | 0.1196 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.09622 | 0.1077 |
Trametinib | 180615_MC_06 | 815 | 0.0905 | 25 | 51 | 4 | 3 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_2 | 76 | 0.0853 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.06190 | 0.0776 |
Trametinib | 180615_MC_06 | 940 | 0.0675 | 23 | 42 | 8 | 5 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_3 | 65 | 0.0647 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04128 | 0.1131 |
Trametinib | 180615_MC_07 | 684 | 0.1320 | 43 | 53 | 6 | 22 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_4 | 96 | 0.1231 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.09968 | 0.0356 |
Trametinib | 180615_MC_07 | 1059 | 0.0731 | 21 | 58 | 7 | 10 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_5 | 79 | 0.0694 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04602 | 0.1436 |
Trametinib | 180615_MC_07 | 785 | 0.1094 | 47 | 44 | 10 | 19 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_6 | 91 | 0.1039 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08048 | 0.0685 |
Trametinib | 180615_MC_08 | 929 | 0.1150 | 45 | 67 | 8 | 3 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_7 | 112 | 0.1076 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08419 | 0.1101 |
Trametinib | 180615_MC_08 | 943 | 0.1131 | 65 | 49 | 8 | 13 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_8 | 114 | 0.1079 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08445 | 0.1139 |
Trametinib | 180615_MC_08 | 891 | 0.1177 | 52 | 59 | 11 | 8 | Trametinib | 0.319359801 | treatment | 72 | 1 | MCF10A-GM_9 | 111 | 0.1108 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08738 | 0.0997 |
Trametinib | 180615_MC_06 | 769 | 0.1676 | 84 | 59 | 8 | 16 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_1 | 143 | 0.1568 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.13340 | 0.0635 |
Trametinib | 180615_MC_06 | 868 | 0.0766 | 33 | 36 | 9 | 11 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_2 | 69 | 0.0736 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.05024 | 0.0932 |
Trametinib | 180615_MC_06 | 854 | 0.0802 | 31 | 40 | 9 | 21 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_3 | 71 | 0.0768 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.05336 | 0.0891 |
Trametinib | 180615_MC_07 | 880 | 0.1082 | 63 | 39 | 8 | 10 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_4 | 102 | 0.1039 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.08047 | 0.0966 |
Trametinib | 180615_MC_07 | 895 | 0.1006 | 39 | 55 | 8 | 21 | Trametinib | 0.998 | treatment | 72 | 1 | MCF10A-GM_5 | 94 | 0.0950 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.07165 | 0.1008 |