LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20358)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trametinib | 180615_MC_06 | 5325 | 0.0179 | 27 | 69 | 4 | 11 | Trametinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_1 | 96 | 0.0177 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00569 | 0.6500 |
Trametinib | 180615_MC_06 | 3992 | 0.0214 | 19 | 67 | 12 | 21 | Trametinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 86 | 0.0211 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00231 | 0.5455 |
Trametinib | 180615_MC_06 | 4454 | 0.0166 | 16 | 58 | 13 | 18 | Trametinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_3 | 74 | 0.0163 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00706 | 0.5844 |
Trametinib | 180615_MC_07 | 4376 | 0.0151 | 4 | 62 | 7 | 3 | Trametinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_4 | 66 | 0.0149 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00854 | 0.5781 |
Trametinib | 180615_MC_07 | 4390 | 0.0155 | 9 | 59 | 13 | 14 | Trametinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_5 | 68 | 0.0153 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00814 | 0.5792 |
Trametinib | 180615_MC_07 | 4768 | 0.0157 | 16 | 59 | 13 | 21 | Trametinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_6 | 75 | 0.0155 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | -0.00791 | 0.6091 |
Trametinib | 180615_MC_08 | 4667 | 0.0277 | 65 | 66 | 6 | 21 | Trametinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_7 | 131 | 0.0273 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00390 | 0.6013 |
Trametinib | 180615_MC_08 | 5134 | 0.0284 | 47 | 100 | 10 | 9 | Trametinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_8 | 147 | 0.0278 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00444 | 0.6364 |
Trametinib | 180615_MC_08 | 4706 | 0.0308 | 61 | 86 | 14 | 12 | Trametinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_9 | 147 | 0.0303 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00689 | 0.6044 |
Trametinib | 180615_MC_06 | 1599 | 0.0411 | 33 | 34 | 3 | 15 | Trametinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_1 | 67 | 0.0402 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.01682 | 0.2557 |
Trametinib | 180615_MC_06 | 1777 | 0.0324 | 15 | 43 | 14 | 7 | Trametinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 58 | 0.0316 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00821 | 0.2862 |
Trametinib | 180615_MC_06 | 1684 | 0.0561 | 64 | 34 | 14 | 8 | Trametinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 98 | 0.0550 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03160 | 0.2706 |
Trametinib | 180615_MC_07 | 1694 | 0.0350 | 19 | 41 | 9 | 13 | Trametinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_4 | 60 | 0.0342 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.01081 | 0.2723 |
Trametinib | 180615_MC_07 | 1741 | 0.0280 | 12 | 37 | 12 | 3 | Trametinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 49 | 0.0274 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.00398 | 0.2802 |
Trametinib | 180615_MC_07 | 1786 | 0.0457 | 52 | 32 | 14 | 8 | Trametinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_6 | 84 | 0.0449 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.02152 | 0.2877 |
Trametinib | 180615_MC_08 | 1486 | 0.0682 | 53 | 52 | 3 | 21 | Trametinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_7 | 105 | 0.0660 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04260 | 0.2350 |
Trametinib | 180615_MC_08 | 1492 | 0.0644 | 15 | 82 | 5 | 4 | Trametinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_8 | 97 | 0.0610 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03765 | 0.2362 |
Trametinib | 180615_MC_08 | 1484 | 0.0611 | 39 | 54 | 7 | 22 | Trametinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_9 | 93 | 0.0590 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03557 | 0.2346 |
Trametinib | 180615_MC_06 | 1059 | 0.0714 | 47 | 32 | 6 | 4 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_1 | 79 | 0.0694 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04602 | 0.1436 |
Trametinib | 180615_MC_06 | 1018 | 0.0666 | 33 | 37 | 7 | 12 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_2 | 70 | 0.0643 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.04094 | 0.1334 |
Trametinib | 180615_MC_06 | 1136 | 0.1018 | 82 | 42 | 14 | 14 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_3 | 124 | 0.0984 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.07501 | 0.1620 |
Trametinib | 180615_MC_07 | 1074 | 0.0662 | 14 | 58 | 7 | 4 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_4 | 72 | 0.0628 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03943 | 0.1473 |
Trametinib | 180615_MC_07 | 1064 | 0.0549 | 10 | 49 | 13 | 16 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_5 | 59 | 0.0525 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.02914 | 0.1449 |
Trametinib | 180615_MC_07 | 1026 | 0.0593 | 36 | 27 | 14 | 12 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_6 | 63 | 0.0579 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.03445 | 0.1354 |
Trametinib | 180615_MC_08 | 880 | 0.1297 | 30 | 88 | 9 | 5 | Trametinib | 0.031603332 | treatment | 72 | 1 | MCF10A-GM_7 | 118 | 0.1182 | 586.3 | 196.0 | 12428 | 298.5 | 0.0234 | 0.09484 | 0.0966 |