Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
HCC1806 Ulixertinib
37.8339826121
 0.7126 0.0346 196.9739 -1.0000 0.6659 0.6968
3.32864045105e-07
BT-20 THZ531
1.39952715577
 0.5663 0.0377 3.3807 -1.0000 1.2457 0.6737
8.31588281125e-07
CAL-51 RO-3306
8.346101408
 0.1772 0.0379 11.9039 -1.0000 3.0941 0.9243
9.77e-15
MCF 10A Rucaparib
365.312204082
 0.8656 0.0388 751.5036 -0.2094 0.4850 0.5902
1.43637187561e-05
BT-549 Rucaparib
inf
 0.8808 0.0404 0.0000 0.9550 0.0100 0.0000
1.0
SUM149PT GSK2334470
25.76380861
 0.6531 0.0406 118.2600 -1.0000 0.7209 0.5628
3.22e-05
HCC38 GSK2334470
362.2276812
 0.7326 0.0411 1000.0000 -0.2309 0.3738 0.3294
0.006774661
T47D Rucaparib
inf
 0.8130 0.0415 0.0000 0.9307 0.0100 0.0000
0.073451061
HCC1419 SHP099
inf
 0.7338 0.0420 0.0000 0.9489 0.0100 0.0000
0.203508371
SUM159PT SHP099
3294.604776
 0.8118 0.0447 1000.0000 0.1710 0.3511 0.3261
0.007206359
HCC1937 SHP099
inf
 0.7745 0.0470 0.0000 0.9312 0.0100 0.0000
1.0
SUM159PT THZ531
1.158729591
 0.6103 0.0475 1.7617 -1.0000 2.6222 0.8700
8.37e-12
HCC38 RO-3306
7.435051917
 -0.2110 0.0493 9.2621 -1.0000 5.0000 0.9513
1.11e-16
HCC1143 Rucaparib
212371.6019
 0.7856 0.0507 630.9562 0.3840 0.2511 0.2497
0.027576264
MDA-MB-157 AZD5363
inf
 0.6671 0.0508 0.0000 0.9480 0.0100 0.0000
0.135243927
HME1 RO-3306
4.087843972
 -0.0172 0.0517 4.0640 0.0144 5.0000 0.9574
1.11e-16
MCF 10A Rucaparib
inf
 0.8695 0.0527 79.7513 0.7576 0.2151 0.3749
0.002812424
HCC1806 AZD5363
1097.05246074
 0.6869 0.0528 1000.0000 0.0138 0.3031 0.3511
0.00448557172627
HCC1143 SHP099
1449.842823
 0.7869 0.0529 1000.0000 0.0556 0.3172 0.3933
0.001935462
HCC1954 RO-3306
6.64148500206
 -0.1134 0.0533 9.5343 -1.0000 3.0385 0.9127
5.7620574978e-14
SUM1315MO2 AZD6738
4.435414924
 -0.1764 0.0538 8.3060 -1.0000 1.7512 0.8774
4.02e-12
HCC1419 Rucaparib
inf
 0.8069 0.0539 0.0000 0.9485 0.0100 0.0000
0.337916631
AU565 AZD6738
9.117192222
 0.2755 0.0564 11.3576 -1.0000 5.0000 0.7383
5.27e-08
CAMA-1 MK 1775
5.412146559
 -0.2519 0.0565 8.5802 -1.0000 2.3841 0.7821
5.36e-09
CAL-51 Ulixertinib
20.08181132
 0.7439 0.0569 48.1868 -0.9997 1.2549 0.4674
0.000380369