Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
MDA-MB-468 Senexin B
1.994645521
 0.1170 0.2810 51.8931 -1.0000 0.3371 0.8162
6.38e-10
CAL-51 Ulixertinib
20.08181132
 0.7439 0.0569 48.1868 -0.9997 1.2549 0.4674
0.000380369
SUM149PT Ulixertinib
2.037761408
 0.1734 0.2350 4.8956 -0.2916 0.5241 0.9161
3.52e-14
MDA-MB-453 GSK2334470
2.045052119
 0.1203 0.2628 36.8285 -1.0000 0.3800 0.7865
4.15e-09
MCF7 Rucaparib
20.52571528
 0.5466 0.0691 95.2231 -1.0000 0.7159 0.5083
0.000140012
HCC38 AZD6738
2.069548926
 -0.2338 0.2316 6.8694 -1.0000 0.9157 0.9405
4.44e-16
SUM159PT MK 1775
2.079002463
 -0.1602 0.2571 9.8880 -1.0000 0.7045 0.8868
1.5e-12
HCC1937 GSK2334470
21.07472865
 0.5809 0.1504 509.5331 -1.0000 0.3449 0.4204
0.00109344
MCF 10A Ribociclib
21.11238563
 0.4876 0.1616 1000.0000 -1.0000 0.2848 0.8863
1.58e-12
HCC1954 Senexin B
211.891286993
 0.4085 0.3284 0.0138 0.4972 0.5378 0.5891
1.48480209144e-05
HCC1143 Rucaparib
212371.6019
 0.7856 0.0507 630.9562 0.3840 0.2511 0.2497
0.027576264
CAL-120 BMS-265246
2.125230074
 0.3446 0.3401 1000.0000 -0.9133 0.1688 0.8479
6e-11
HCC1428 AZD2014
2.19e-05
 -0.5555 1.2048 0.0005 -0.5838 0.2503 0.4940
0.000200146
Hs 578T SHP099
222.1051901
 0.5953 0.1451 1000.0000 -0.2087 0.2319 0.7318
7.17e-08
BT-20 Senexin B
2.23064370113
 0.0956 0.2772 71.2131 -1.0000 0.3172 0.7918
3.02648173189e-09
SUM1315MO2 SHP099
22.32790504
 0.4783 0.1197 419.3194 -1.0000 0.3746 0.3197
0.008107411
CAL-51 GSK2334470
22.73047392
 0.8334 0.0336 53.5738 -0.9998 1.2813 0.2592
0.023515658
MDA-MB-134-VI LY3023414
2.28e-05
 -0.9131 1.4118 0.0019 -1.0000 0.2471 0.8907
9.62e-13
SUM149PT Ribociclib
229.6984296
 0.5649 0.1855 1.4808 0.4031 0.3252 0.8653
1.31e-11
MDA-MB-468 AZD5363
23.1790046
 0.5103 0.1319 558.0456 -1.0000 0.3453 0.7227
1.09e-07
SUM1315MO2 Ribociclib
2.417104164
 0.4065 0.3624 0.0997 0.2788 0.2557 0.5827
1.8e-05
Hs 578T Senexin B
2420179.078
 0.7716 0.1355 1000.0000 0.3393 0.1457 0.6302
3.97e-06
HCC1500 LY3023414
2.44e-06
 -0.9965 1.9835 0.0000 -0.9955 0.7773 0.6628
1.25e-06
HCC1419 MK 1775
2.452749667
 -0.0791 0.2879 12.3795 -1.0000 0.6786 0.7916
3.06e-09
CAMA-1 Ulixertinib
2.566161953
 0.1288 0.2586 42.4009 -1.0000 0.3917 0.5616
3.34e-05