Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
CAMA-1 Rucaparib
inf
 0.8528 0.1254 0.0108 0.8301 5.0000 0.2588
0.023653062
HCC1954 Rucaparib
inf
 0.8492 0.0892 0.0000 0.9429 0.0100 0.0000
1.0
CAL-120 Senexin B
inf
 0.8437 0.1267 0.0000 0.8683 0.0100 0.0000
0.139800748
MDA-MB-436 SHP099
inf
 0.8419 -0.0182 0.0000 0.9962 0.0100 0.0000
0.527646554
HCC1806 GSK2334470
44.5159354048
 0.8389 0.0198 86.1125 -0.5419 1.1127 0.3134
0.00908806432112
CAL-51 GSK2334470
22.73047392
 0.8334 0.0336 53.5738 -0.9998 1.2813 0.2592
0.023515658
MCF7 SHP099
inf
 0.8331 0.0289 0.0000 0.9643 0.0100 0.0000
0.073472433
BT-549 SHP099
2619.73295091
 0.8306 0.0279 21.5161 0.4877 0.7710 0.6498
2.01339374906e-06
MCF 10A GSK2334470
127.2855112
 0.8292 0.0271 886.4613 -0.9671 0.5546 0.7883
3.72e-09
MCF 10A Senexin B
13.2364754711
 0.8231 -0.0310 16.5655 -1.0000 4.8970 0.5533
1.42287035656e-05
AU565 Senexin B
inf
 0.8184 0.1417 0.0000 0.8787 0.0100 0.0000
0.163234872
T47D Rucaparib
inf
 0.8130 0.0415 0.0000 0.9307 0.0100 0.0000
0.073451061
SUM159PT SHP099
3294.604776
 0.8118 0.0447 1000.0000 0.1710 0.3511 0.3261
0.007206359
HCC1806 Senexin B
inf
 0.8083 0.1042 0.1453 0.7979 0.4002 0.4857
0.000245355132328
MDA-MB-134-VI SHP099
-inf
 0.8081
HCC1419 Rucaparib
inf
 0.8069 0.0539 0.0000 0.9485 0.0100 0.0000
0.337916631
CAL-120 AZD5363
51.38789856
 0.7988 0.0266 243.4579 -1.0000 0.7063 0.4791
0.0002881
MDA-MB-468 Ribociclib
inf
 0.7972 0.0091 0.0000 0.9779 0.0100 0.0000
1.0
CAL-120 SHP099
13.63352074
 0.7924 0.0042 16.9837 -1.0000 5.0000 0.4392
0.000724955
SK-BR-3 Senexin B
inf
 0.7921 0.1660 0.0000 0.8353 0.0100 0.0000
1.0
MCF 10A AZD5363
61.7286667806
 0.7916 0.0307 77.1806 -0.0911 0.7489 0.9088
9.96980276113e-14
HCC1143 SHP099
1449.842823
 0.7869 0.0529 1000.0000 0.0556 0.3172 0.3933
0.001935462
HCC1143 Rucaparib
212371.6019
 0.7856 0.0507 630.9562 0.3840 0.2511 0.2497
0.027576264
HME1 Senexin B
inf
 0.7841 0.1891 0.0158 0.7123 0.2814 0.4068
0.001463753
SUM159PT Rucaparib
1.81722e+11
 0.7797 0.0896 999.9789 0.4809 0.1718 0.3608
0.003721786