Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20355)

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Cell Small Molecule GR50 GRmax GR_AOC GEC50 GRinf GR Hill Coefficient GR r2 pval_GR
HCC1500 Alvocidib
-inf
 -0.9990
HCC1500 GSK2334470
-inf
 -0.7194
HCC1500 Ribociclib
inf
 1.0336 0.4512 0.0000 0.5131 0.0100 0.0000
1.0
HCC1500 LY3023414
2.44e-06
 -0.9965 1.9835 0.0000 -0.9955 0.7773 0.6628
1.25e-06
HCC1500 RO-3306
-inf
 -0.9896
HCC1500 Rucaparib
#NAME?
 1.0742 0.0000 0.1000 0.0100
HCC1500 Senexin B
-inf
 -0.9794
HCC1500 SHP099
-inf
 -0.1868
HCC1500 THZ1
-inf
 -0.9999
HCC1500 THZ531
-inf
 -0.9990
HCC1937 MK 1775
0.008394634
 -0.1880 0.6919 0.0152 -0.1214 0.3668 0.8610
1.94e-11
HCC1937 AZD2014
0.030181855
 0.3561 0.4941 0.0005 0.3576 0.3088 0.5080
0.00014109
HCC1937 AZD5363
12.85319785
 0.4773 0.3596 0.0112 0.4671 0.3863 0.5345
7.07e-05
HCC1937 AZD6738
7.75547782
 0.2590 -0.1086 19.3707 -0.9926 1.1948 0.4429
0.00046323
HCC1937 BMS-265246
0.000340758
 -0.0634 0.9143 0.0005 -0.0734 0.4108 0.8462
6.89e-11
HCC1937 Ulixertinib
15.02907863
 0.4534 0.1152 180.4631 -1.0000 0.4420 0.6441
2.46e-06
HCC1937 Alvocidib
0.166518918
 -0.2096 0.2105 0.2327 -0.3409 1.5542 0.9076
1.17e-13
HCC1937 GSK2334470
21.07472865
 0.5809 0.1504 509.5331 -1.0000 0.3449 0.4204
0.00109344
HCC1937 Ribociclib
inf
 0.9905 -0.0141 0.0000 0.9898 0.0100 0.0000
1.0
HCC1937 LY3023414
0.148759974
 -0.0889 0.4702 448.2987 -1.0000 0.1371 0.5290
8.17e-05
HCC1937 RO-3306
5.195291201
 -0.1516 0.1187 9.2676 -1.0000 1.8982 0.8820
2.49e-12
HCC1937 Rucaparib
inf
 0.7658 0.0636 0.0095 0.8675 5.0000 0.2293
0.038523875
HCC1937 Senexin B
5.024951315
 0.4311 0.2642 1000.0000 -0.9063 0.1954 0.7116
1.77e-07
HCC1937 SHP099
inf
 0.7745 0.0470 0.0000 0.9312 0.0100 0.0000
1.0
HCC1937 THZ1
0.064677099
 -0.3919 0.3250 0.0812 -0.3041 2.0906 0.9470
1.11e-16