Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
SK-BR-3 Bleomycin
10.0
Radiation
Misc
 0.1871 0.22301
SK-BR-3 Ipatasertib
0.001
AKT
PI3K/mTOR
 1.0406 -0.00019
SK-BR-3 Ipatasertib
0.0031623
AKT
PI3K/mTOR
 1.0766 -0.00484
SK-BR-3 Ipatasertib
0.01
AKT
PI3K/mTOR
 1.0404 0.00786
SK-BR-3 Ipatasertib
0.031623
AKT
PI3K/mTOR
 1.0397 0.01094
SK-BR-3 Ipatasertib
0.1
AKT
PI3K/mTOR
 0.9410 0.00816
SK-BR-3 Ipatasertib
0.31623
AKT
PI3K/mTOR
 0.7553 0.02927
SK-BR-3 Ipatasertib
1.0
AKT
PI3K/mTOR
 0.6485 0.02750
SK-BR-3 Ipatasertib
3.1623
AKT
PI3K/mTOR
 0.5842 0.05390
SK-BR-3 Ipatasertib
10.0
AKT
PI3K/mTOR
 0.3560 0.09589
SK-BR-3 Alpelisib
0.001
PI3Ka
PI3K/mTOR
 0.9591 0.00423
SK-BR-3 Alpelisib
0.0031623
PI3Ka
PI3K/mTOR
 0.9575 0.00305
SK-BR-3 Alpelisib
0.01
PI3Ka
PI3K/mTOR
 0.9529 0.01481
SK-BR-3 Alpelisib
0.031623
PI3Ka
PI3K/mTOR
 0.8862 0.01542
SK-BR-3 Alpelisib
0.1
PI3Ka
PI3K/mTOR
 0.6971 0.03031
SK-BR-3 Alpelisib
0.31623
PI3Ka
PI3K/mTOR
 0.4854 0.05504
SK-BR-3 Alpelisib
1.0
PI3Ka
PI3K/mTOR
 0.3638 0.07948
SK-BR-3 Alpelisib
3.1623
PI3Ka
PI3K/mTOR
 0.2183 0.11201
SK-BR-3 Alpelisib
10.0
PI3Ka
PI3K/mTOR
 -0.1428 0.27943
SK-BR-3 Taselisib
0.001
PI3Ka, g, d
PI3K/mTOR
 0.8196 0.02009
SK-BR-3 Taselisib
0.0031623
PI3Ka, g, d
PI3K/mTOR
 0.6138 0.04383
SK-BR-3 Taselisib
0.01
PI3Ka, g, d
PI3K/mTOR
 0.4000 0.08368
SK-BR-3 Taselisib
0.031623
PI3Ka, g, d
PI3K/mTOR
 0.1745 0.12889
SK-BR-3 Taselisib
0.1
PI3Ka, g, d
PI3K/mTOR
 0.0683 0.16907
SK-BR-3 Taselisib
0.31623
PI3Ka, g, d
PI3K/mTOR
 0.0386 0.18419