Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
---|---|---|---|---|---|---|
SK-BR-3 | A-1210477 | 0.0031623 | Mcl-1 | Misc | 0.9516 | -0.00496 |
SK-BR-3 | A-1210477 | 0.01 | Mcl-1 | Misc | 0.9728 | 0.00932 |
SK-BR-3 | A-1210477 | 0.031623 | Mcl-1 | Misc | 0.9500 | -0.00408 |
SK-BR-3 | A-1210477 | 0.1 | Mcl-1 | Misc | 1.0436 | 0.00001 |
SK-BR-3 | A-1210477 | 0.31623 | Mcl-1 | Misc | 0.9734 | -0.00177 |
SK-BR-3 | A-1210477 | 1.0 | Mcl-1 | Misc | 0.9969 | -0.00665 |
SK-BR-3 | A-1210477 | 3.1623 | Mcl-1 | Misc | 0.9958 | -0.00690 |
SK-BR-3 | A-1210477 | 10.0 | Mcl-1 | Misc | 0.6275 | 0.05832 |
SK-BR-3 | Olaparib | 0.001 | PARP | Misc | 1.0881 | 0.00188 |
SK-BR-3 | Olaparib | 0.0031623 | PARP | Misc | 0.9923 | 0.01337 |
SK-BR-3 | Olaparib | 0.01 | PARP | Misc | 1.0529 | 0.00896 |
SK-BR-3 | Olaparib | 0.031623 | PARP | Misc | 1.0321 | 0.01045 |
SK-BR-3 | Olaparib | 0.1 | PARP | Misc | 1.0506 | 0.01370 |
SK-BR-3 | Olaparib | 0.31623 | PARP | Misc | 0.9298 | 0.01083 |
SK-BR-3 | Olaparib | 1.0 | PARP | Misc | 0.9394 | 0.00719 |
SK-BR-3 | Olaparib | 3.1623 | PARP | Misc | 0.8559 | 0.02556 |
SK-BR-3 | Olaparib | 10.0 | PARP | Misc | 0.5653 | 0.06430 |
SK-BR-3 | Bleomycin | 0.0010833 | Radiation | Misc | 1.0381 | -0.00525 |
SK-BR-3 | Bleomycin | 0.0033333 | Radiation | Misc | 1.0613 | -0.00465 |
SK-BR-3 | Bleomycin | 0.01 | Radiation | Misc | 0.9122 | 0.00535 |
SK-BR-3 | Bleomycin | 0.031667 | Radiation | Misc | 0.9250 | 0.01018 |
SK-BR-3 | Bleomycin | 0.1 | Radiation | Misc | 0.9098 | 0.01503 |
SK-BR-3 | Bleomycin | 0.31623 | Radiation | Misc | 0.6910 | 0.05073 |
SK-BR-3 | Bleomycin | 1.0 | Radiation | Misc | 0.5188 | 0.12104 |
SK-BR-3 | Bleomycin | 3.1623 | Radiation | Misc | 0.3155 | 0.14104 |