Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
SK-BR-3 ABT-737
0.031623
Bcl2/XL
Misc
 1.0625 -0.00170
SK-BR-3 ABT-737
0.1
Bcl2/XL
Misc
 1.0625 -0.00204
SK-BR-3 ABT-737
0.31623
Bcl2/XL
Misc
 0.9911 0.00195
SK-BR-3 ABT-737
1.0
Bcl2/XL
Misc
 1.0019 -0.00495
SK-BR-3 ABT-737
3.1623
Bcl2/XL
Misc
 1.0068 0.00549
SK-BR-3 ABT-737
10.0
Bcl2/XL
Misc
 0.9470 0.01997
SK-BR-3 Vorinostat
0.001
HDAC
Misc
 0.9897 0.00371
SK-BR-3 Vorinostat
0.0031623
HDAC
Misc
 1.0589 -0.01158
SK-BR-3 Vorinostat
0.01
HDAC
Misc
 0.9606 -0.00028
SK-BR-3 Vorinostat
0.031623
HDAC
Misc
 1.1091 0.00223
SK-BR-3 Vorinostat
0.1
HDAC
Misc
 1.1297 -0.00228
SK-BR-3 Vorinostat
0.31623
HDAC
Misc
 0.9767 0.02265
SK-BR-3 Vorinostat
1.0
HDAC
Misc
 0.2317 0.13720
SK-BR-3 Vorinostat
3.1623
HDAC
Misc
 -0.4076 0.53950
SK-BR-3 Vorinostat
10.0
HDAC
Misc
 -0.6322 0.68923
SK-BR-3 Luminespib
0.0001
HSP90
Misc
 0.9574 0.00344
SK-BR-3 Luminespib
0.00031623
HSP90
Misc
 1.0229 -0.00193
SK-BR-3 Luminespib
0.001
HSP90
Misc
 0.8819 0.01521
SK-BR-3 Luminespib
0.0031623
HSP90
Misc
 0.2897 0.06796
SK-BR-3 Luminespib
0.01
HSP90
Misc
 -0.0896 0.15871
SK-BR-3 Luminespib
0.031623
HSP90
Misc
 -0.0993 0.19348
SK-BR-3 Luminespib
0.1
HSP90
Misc
 -0.0865 0.18330
SK-BR-3 Luminespib
0.31623
HSP90
Misc
 -0.0766 0.17436
SK-BR-3 Luminespib
1.0
HSP90
Misc
 -0.0656 0.19462
SK-BR-3 A-1210477
0.001
Mcl-1
Misc
 0.9811 -0.00772