Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Primary Target | Pathway | Mean Normalized Growth Rate Inhibition Value | Increased Fraction Dead |
|---|---|---|---|---|---|---|
| BT-20 | Taxol | 0.00031623 | Chemo | Chemotherapy | 1.0128 | 0.00568 |
| BT-20 | Taxol | 0.001 | Chemo | Chemotherapy | 0.8429 | 0.05831 |
| BT-20 | Taxol | 0.0031623 | Chemo | Chemotherapy | 0.1531 | 0.33718 |
| BT-20 | Taxol | 0.01 | Chemo | Chemotherapy | -0.4404 | 0.67612 |
| BT-20 | Taxol | 0.031623 | Chemo | Chemotherapy | -0.5117 | 0.70834 |
| BT-20 | Taxol | 0.1 | Chemo | Chemotherapy | -0.5245 | 0.72716 |
| BT-20 | Taxol | 0.31623 | Chemo | Chemotherapy | -0.5527 | 0.73180 |
| BT-20 | Taxol | 1.0 | Chemo | Chemotherapy | -0.5760 | 0.75435 |
| BT-20 | Topotecan | 0.0010833 | Topo I | Chemotherapy | 0.9587 | 0.00163 |
| BT-20 | Topotecan | 0.0033333 | Topo I | Chemotherapy | 0.8298 | 0.01267 |
| BT-20 | Topotecan | 0.01 | Topo I | Chemotherapy | 0.5944 | 0.03501 |
| BT-20 | Topotecan | 0.031667 | Topo I | Chemotherapy | 0.0778 | 0.17752 |
| BT-20 | Topotecan | 0.1 | Topo I | Chemotherapy | -0.1916 | 0.38062 |
| BT-20 | Topotecan | 0.31623 | Topo I | Chemotherapy | -0.4294 | 0.62043 |
| BT-20 | Topotecan | 1.0 | Topo I | Chemotherapy | -0.5883 | 0.73829 |
| BT-20 | Topotecan | 3.1623 | Topo I | Chemotherapy | -0.6410 | 0.75823 |
| BT-20 | Topotecan | 10.0 | Topo I | Chemotherapy | -0.6062 | 0.69009 |
| BT-20 | Etoposide | 0.0010833 | Topo II | Chemotherapy | 1.0323 | -0.00511 |
| BT-20 | Etoposide | 0.0033333 | Topo II | Chemotherapy | 0.9830 | -0.00083 |
| BT-20 | Etoposide | 0.01 | Topo II | Chemotherapy | 1.0035 | 0.00069 |
| BT-20 | Etoposide | 0.031667 | Topo II | Chemotherapy | 0.9470 | 0.00100 |
| BT-20 | Etoposide | 0.1 | Topo II | Chemotherapy | 0.8121 | 0.02092 |
| BT-20 | Etoposide | 0.31623 | Topo II | Chemotherapy | 0.5057 | 0.06328 |
| BT-20 | Etoposide | 1.0 | Topo II | Chemotherapy | -0.0240 | 0.21538 |
| BT-20 | Etoposide | 3.1623 | Topo II | Chemotherapy | -0.1928 | 0.36551 |