Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
BT-20 Dinaciclib
0.0031623
pan CDK
Cell cycle
1.1052 -0.01052
BT-20 Dinaciclib
0.01
pan CDK
Cell cycle
0.9207 0.01310
BT-20 Dinaciclib
0.031623
pan CDK
Cell cycle
-0.2318 0.45734
BT-20 Dinaciclib
0.1
pan CDK
Cell cycle
-0.6475 0.78890
BT-20 Dinaciclib
0.31623
pan CDK
Cell cycle
-0.6706 0.80415
BT-20 Dinaciclib
1.0
pan CDK
Cell cycle
-0.6979 0.82310
BT-20 Cisplatin
0.0010833
Chemo
Chemotherapy
1.0413 -0.00632
BT-20 Cisplatin
0.0033333
Chemo
Chemotherapy
0.9228 0.00083
BT-20 Cisplatin
0.01
Chemo
Chemotherapy
0.9290 0.00291
BT-20 Cisplatin
0.031667
Chemo
Chemotherapy
1.0207 -0.00542
BT-20 Cisplatin
0.1
Chemo
Chemotherapy
0.9474 0.00664
BT-20 Cisplatin
0.31623
Chemo
Chemotherapy
0.7633 0.01654
BT-20 Cisplatin
1.0
Chemo
Chemotherapy
0.3472 0.06425
BT-20 Cisplatin
3.1623
Chemo
Chemotherapy
0.0662 0.10679
BT-20 Cisplatin
10.0
Chemo
Chemotherapy
-0.3367 0.52833
BT-20 Doxorubicin
0.00031623
Chemo
Chemotherapy
0.9030 -0.00402
BT-20 Doxorubicin
0.001
Chemo
Chemotherapy
0.9704 0.00469
BT-20 Doxorubicin
0.0031623
Chemo
Chemotherapy
0.8826 0.01682
BT-20 Doxorubicin
0.01
Chemo
Chemotherapy
0.4333 0.12869
BT-20 Doxorubicin
0.031623
Chemo
Chemotherapy
-0.1440 0.31126
BT-20 Doxorubicin
0.1
Chemo
Chemotherapy
-0.2015 0.36820
BT-20 Doxorubicin
0.31623
Chemo
Chemotherapy
-0.3158 0.50771
BT-20 Doxorubicin
1.0
Chemo
Chemotherapy
-0.4813 0.65568
BT-20 Doxorubicin
3.1623
Chemo
Chemotherapy
-0.4368 0.73288
BT-20 Taxol
0.0001
Chemo
Chemotherapy
0.8501 0.01100