Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 1 of 2: Normalized growth rate inhibition values - Dataset (ID:20343)

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Cell Small Molecule Small Mol Concentration (uM) Primary Target Pathway Mean Normalized Growth Rate Inhibition Value Increased Fraction Dead
BT-20 Cediranib
0.0031623
VEGFR/cKIT
RTK
 1.0844 -0.00715
BT-20 Cediranib
0.01
VEGFR/cKIT
RTK
 1.0841 -0.00444
BT-20 Cediranib
0.031623
VEGFR/cKIT
RTK
 1.0909 -0.00420
BT-20 Cediranib
0.1
VEGFR/cKIT
RTK
 1.0807 -0.00031
BT-20 Cediranib
0.31623
VEGFR/cKIT
RTK
 1.0445 -0.00133
BT-20 Cediranib
1.0
VEGFR/cKIT
RTK
 0.9874 0.01373
BT-20 Cediranib
3.1623
VEGFR/cKIT
RTK
 0.8266 0.01269
BT-20 Cediranib
10.0
VEGFR/cKIT
RTK
 0.2210 0.12967
BT-20 Cabozantinib
0.001
VEGFR2/MET
RTK
 0.9762 0.00295
BT-20 Cabozantinib
0.0031623
VEGFR2/MET
RTK
 0.9808 -0.00257
BT-20 Cabozantinib
0.01
VEGFR2/MET
RTK
 1.0367 0.00057
BT-20 Cabozantinib
0.031623
VEGFR2/MET
RTK
 1.0589 -0.00313
BT-20 Cabozantinib
0.1
VEGFR2/MET
RTK
 1.0915 -0.00763
BT-20 Cabozantinib
0.31623
VEGFR2/MET
RTK
 1.0571 -0.00715
BT-20 Cabozantinib
1.0
VEGFR2/MET
RTK
 1.0886 -0.00310
BT-20 Cabozantinib
3.1623
VEGFR2/MET
RTK
 0.9431 0.00847
BT-20 Cabozantinib
10.0
VEGFR2/MET
RTK
 -0.2030 0.40043
BT-549 Abemaciclib
0.001
CDK4/6
Cell cycle
 0.9933 -0.00259
BT-549 Abemaciclib
0.0031623
CDK4/6
Cell cycle
 1.0379 -0.00284
BT-549 Abemaciclib
0.01
CDK4/6
Cell cycle
 1.0191 0.00387
BT-549 Abemaciclib
0.031623
CDK4/6
Cell cycle
 0.9941 -0.00435
BT-549 Abemaciclib
0.1
CDK4/6
Cell cycle
 0.9609 0.00055
BT-549 Abemaciclib
0.31623
CDK4/6
Cell cycle
 0.9772 -0.01089
BT-549 Abemaciclib
1.0
CDK4/6
Cell cycle
 0.8898 0.00509
BT-549 Abemaciclib
3.1623
CDK4/6
Cell cycle
 0.5941 0.02941